Malaria case management in Papua New Guinea following the introduction of a revised treatment protocol (Publications)
fever or suspected malaria patients and via an interviewer administered questionnaire completed with the officer in charge of each participating health care facility. RESULTS: Malaria rapid diagnostic tests [...] 445) were tested for malaria by RDT and 39% prescribed an anti-malarial, inclusive of 98.2% of RDT positive patients and 19.8% of RDT negative cases. The availability and use of malaria RDTs was greater in [...] CONCLUSIONS: PNG has achieved high coverage of malaria RDTs and AL at the...
Naturally acquired immune responses to <em>P. vivax</em> merozoite surface protein 3alpha and merozoite surface protein 9 are associated with reduced... (Publications)
is the most geographically widespread human malaria parasite. Cohort studies in Papua New Guinea have identified a rapid onset of immunity against vivax-malaria in children living in highly endemic areas [...] and Merozoite Surface Protein 9 (PvMSP9) were measured and related to prospective risk of P. vivax malaria during 16 months of active follow-up. Overall, there was a low prevalence of antibodies to PvMSP3alpha [...] PvMSP9 N-terminus (aIRR = 0.68, p = 0.035) were associated with protection...
The contribution of reduction in malaria as a cause of rapid decline of under-five mortality: evidence from the Rufiji Health and Demographic... (Publications)
settings. Malaria-related mortality is known to be a major component of childhood causes of death and malaria remains a major focus of health interventions. The paper explored the contribution of malaria relative [...] remained the leading cause of death for neonates, malaria remains as the leading cause of death for post-neonates followed by pneumonia. However, declines in malaria death rates accounted for 49.9% of the observed [...] accounted for only 19.9%. CONCLUSION: To achieve MDG 4 in mal...
Investigating mosquito net durability for malaria control in Tanzania - attrition, bioefficacy, chemistry, degradation and insecticide resistance... (Publications)
(LLINs) are one of the major malaria vector control tools, with most countries adopting free or subsidised universal coverage campaigns of populations at-risk from malaria. It is essential to understand [...] data sets to provide GIS maps for use in health surveillance and decision making by the National Malaria Control Program (NMCP). DISCUSSION: The data will be of importance to policy makers and vector control [...] for the maintenance of high and cost-effective coverage and to maximise...
Transmission of malaria in relation to distribution and coverage of long-lasting insecticidal nets in central Côte d'Ivoire (Publications)
BACKGROUND: The use of long-lasting insecticidal nets (LLINs) is an effective malaria control strategy. However, there are challenges to achieve high coverage, such as distribution sustainability, and [...] study assessed the effect of LLINs coverage and contextual factors on entomological indicators of malaria in rural Côte d'Ivoire. METHODS: The study was carried out between July 2009 and May 2012 in three [...] of central Côte d'Ivoire. In Bozi and Yoho, LLINs were distributed free of charge...
Community response to intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (Publications)
Africa this article aims to investigate the acceptability of intermittent preventive treatment of malaria in infants (IPTi) in Papua New Guinea (PNG). METHODS: A questionnaire was administered to mothers [...] is little evidence that IPTi has negative impacts on attitudes to EPI, EPI adherence or existing malaria prevention practices. CONCLUSION: The degree of similarity between findings from the acceptability [...] health cultures, appears to be accepted easily and has little impact on...
Improving health worker adherence to malaria treatment guidelines in Papua New Guinea: feasibility and acceptability of a text message reminder... (Publications)
whether a text message reminder service designed to support health worker adherence to a revised malaria treatment protocol is feasible and acceptable in Papua New Guinea (PNG). The study took place in [...] resources. In conclusion, a text message reminder service to support health worker adherence to the new malaria treatment protocol is feasible and acceptable in PNG. A rigorous pragmatic, effectiveness trial would
Potential causes and consequences of behavioural resilience and resistance in malaria vector populations: a mathematical modelling analysis (Publications)
evade fatal exposure to insecticidal nets and sprays represents the primary obstacle to eliminating malaria. However, it remains unclear which behaviours are most important for buffering mosquito and parasite
Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young... (Publications)
BACKGROUND: A malaria vaccine could be an important addition to current control strategies. We report the safety and vaccine efficacy (VE) of the RTS,S/AS01 vaccine during 18 mo following vaccination at [...] at 11 African sites with varying malaria transmission. METHODS AND FINDINGS: 6,537 infants aged 6-12 wk and 8,923 children aged 5-17 mo were randomized to receive three doses of RTS,S/AS01 or comparator [...] comparator vaccine. VE against clinical malaria in children during the 18 mo after...
The exit interview as a proxy measure of malaria case management practice: sensitivity and specificity relative to direct observation (Publications)
sensitivity and specificity of exit interviews as a measure of malaria case management practice as compared to direct observation.MethodsThe malaria case management of 1654 febrile patients attending 110 health [...] specificity from 70.6% to 98.1%.ConclusionThe exit interview appears to be a valid measure of objective malaria case management practices such as the completion of a diagnostic test or the provision of antimalarial [...] but may be a less valid measure of low frequency, subjective...
