Preclinical profiling of virosomally formulated B-cell epitope mimetics derived from the novel key malaria vaccine candidates CyRPA and RH5 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/preclinical-profiling-of-virosomally-formulated-b-cell-epitope-mimetics-derived-from-the-novel-key-malaria-vaccine-candidates-cyrpa-and-rh5
Clinical testing of two components for a synthetic peptide-based virosomal malaria vaccine has yielded promising results, encouraging the search for additional components for inclusion in a final multivalent
Impact of systems failures in malaria service delivery in Africa (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/impact-of-systems-failures-in-malaria-service-delivery-in-africa
evaluate effective coverage of malaria curative interventions in Sub-Saharan Africa. We quantify excess morbidity and mortality induced by sub-optimal distribution of malaria services incorporating, among [...] Malaria treatment provides individual benefits by curing infection and preventing progression to severe disease. Treatment also provides community-level benefits by reducing the infectious reservoir. However [...] ent and the extent of health benefits achieved by such care, thus has...
Understanding the human, parasite, vector and environmental interactions driving residual malaria transmission in Papua New Guinea (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/understanding-the-human-parasite-vector-and-environmental-interactions-driving-residual-malaria-transmission-in-papua-new-guinea
The scale-up of malaria control in Papua New Guinea (PNG) has resulted in a significant reduction in the nationwide prevalence and incidence of malaria. However, this effect has not been uniform across [...] address this knowledge gap by: measuring the prevalence and distribution of malaria infection to assess the magnitude of residual malaria at the time of study, studying the Anopheles vectors to characterize local [...] heterogeneity in malaria transmission and the its driving factors is...
Malaria Course in Tanzania and Laos (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/malaria-course-in-tanzania-and-laos
activities in the field of malaria. To improve skills in time management, presenting, writing research proposals. At the end of the course, the participants should be able to manage malaria issues more effectively [...] A four-week postgraduate course on malaria prevention, control & elimination. Course objectives are: Building capacity by reinforcing knowledge and expertise of persons involved in the care of patients
MalCommit - Understanding Sexual Commitment and Early Differentiation of Malaria Transmission Stages (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/malcommit-understanding-sexual-commitment-and-early-differentiation-of-malaria-transmission-stages
The project aims to understand the processes responsible for the differentiation of asexual malaria blood stage parasites into sexual forms. The anticipated results may open up new avenues for the development
The useful life of bednets for malaria control in Tanzania: Attrition, Bioefficacy, Chemistry, Damage and Insecticide Resistance. (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/the-useful-life-of-bednets-for-malaria-control-in-tanzania-attrition-bioefficacy-chemistry-damage-and-insecticide-resistance
life of bednets for malaria control in Tanzania: Attrition, Bioefficacy, Chemistry, Damage and insecticide Resistance. Long-Lasting Insecticidal Nets (LLINs) are the front line malaria vector control tool [...] practice for the maintenance of high and cost-effective coverage and to maximise current gains in malaria control. We will make the data available to stakeholders including NMCP and their collaborators:
Understanding heterogeneities in the epidemiology of malaria in Papua New Guinea (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/understanding-heterogeneities-in-the-epidemiology-of-malaria-in-papua-new-guinea
Background Malaria has been endemic across most parts of Papua New Guinea (PNG) at endemicity levels comparable to sub-Saharan Africa. The National Malaria Control Program (NMCP) has managed to substantially [...] impact of malaria control interventions and underlying secular trends. Drivers of change, and reasons for differences between sites will be investigated. 2) Geo-referenced data on clinical malaria cases will [...] ongoing mathematical modelling of heterogeneities in malaria dynamics at...