Mathematical modelling of the impact of expanding levels of malaria control interventions on <em>Plasmodium vivax</em> (Publications)
Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and vector control strateg
C-H activation enables a concise total synthesis of quinine and analogues with enhanced antimalarial activity (Publications)
We report a novel approach to the classical natural product quinine that is based on two stereoselective key steps, namely a C-H activation and an aldol reaction, to unite the two heterocyclic moietie
Does the DOSPERT scale predict risk taking behaviour during travel? A study using smartphones (Publications)
Background: Despite the continuing growth of international tourism, very little research has been done on the link between individual risk attitudes and health behaviours during travel. Our study uses
Barriers to access improved water and sanitation in poor peri-urban settlements of Abidjan, Côte d'Ivoire (Publications)
Achieving access to safe water and sanitation still pose major challenges in urban areas of sub-Saharan Africa countries, despite all the progress achieved in the last decade. This study assessed the
Boosting effect of IL-7 in interferon gamma release assays to diagnose <em>Mycobacterium tuberculosis</em> infection (Publications)
BACKGROUND: A quarter of the world's population is estimated to be infected with Myobacterium tuberculosis (Mtb). Infection is detected by immune response to M. tuberculosis antigens using either tube
Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins (Publications)
Cyclic peptides containing non-proteinogenic amino acids often exhibit a broad bioactivity spectrum and many have entered clinical trials with good prospects for drug development. We recently reported
Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission (Publications)
BACKGROUND: Current strategies to control mosquito-transmitted infections use insecticides targeted at various stages of the mosquito life-cycle. Control is increasingly compromised by the evolution o