Antiplasmodial imidazopyridazines: structure-activity relationship studies lead to the identification of analogues with improved solubility and hERG... (Publications)
3,6-Diarylated imidazopyridazines have recently been shown to possess good in vitro antiplasmodial and in vivo antimalarial activity. However, frontrunner compounds have been associated with poor solu
Cell penetration, herbicidal activity, and <em>in-vivo</em>-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived... (Publications)
Oligo-arginines are thoroughly studied cell-penetrating peptides (CPPs, Figures 1 and 2). Previous in-vitro investigations with the octaarginine salt of the phosphonate fosmidomycin (herbicide and ant
Creation of the WHO Indicators of Infant and Young Child Development (IYCD): metadata synthesis across 10 countries (Publications)
Background: Renewed global commitment to the improvement of early child development outcomes, as evidenced by the focus of the United Nations Sustainable Development Goal 4, highlights an increased ne
Use of recombinant ApxIV in serodiagnosis of <em>Actinobacillus pleuropneumoniae</em> infections, development and prevalidation of the ApxIV ELISA (Publications)
Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, which causes worldwide severe losses in pig farming. The virulence of the 15 serotypes of A. pleuropneumoniae is ma
Leptospira seroprevalence and risk factors in health centre patients in Hoima District, Western Uganda (Publications)
BACKGROUND: The burden of human leptospirosis in Uganda is unknown. We estimated the seroprevalence of Leptospira antibodies, probable acute/recent leptospirosis, and risk factors for seropositivity i