Detection and characterization of ESBL-producing<em> Escherichia coli</em> from humans and poultry in Ghana (Publications)
Introduction: The increasing incidence of infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in sub-Saharan Africa is of serious concern. Studies from countries wi
Gender differences in the association between life history of body silhouettes and asthma incidence: results from the SAPALDIA cohort study (Publications)
Background: The association of obesity and asthma has been described in children and adults. However, whether a different life course of weight in men and women may explain gender differences in asthm
Modelling to inform prophylaxis regimens to prevent human rabies (Publications)
BACKGROUND: The Strategic Advisory Group of Experts (SAGE) Working Group on rabies vaccines and immunoglobulins was established in 2016 to develop practical and feasible recommendations for prevention
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background (Publications)
The predisposition of parasites acquiring artemisinin resistance still remains unclear beyond the mutations in Pfk13 gene and modulation of the unfolded protein response pathway. To explore the chain
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa (Publications)
There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reco
Integrated <em>Aedes</em> management for the control of <em>Aedes</em>-borne diseases (Publications)
BACKGROUND: Diseases caused by Aedes-borne viruses, such as dengue, Zika, chikungunya, and yellow fever, are emerging and reemerging globally. The causes are multifactorial and include global trade, i
Drug discovery for kinetoplastid diseases: future directions (Publications)
Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis (particularly on the Indian subcontinent) an
HIV infection functionally impairs <em>Mycobacterium tuberculosis</em>-specific CD4 and CD8 T-cell responses (Publications)
HIV infection is the major risk factor predisposing for Mycobacterium tuberculosis (Mtb) progression from latent tuberculosis infection (LTBI) to tuberculosis disease (TB). Since long-term treated avi