Female predominance and transmission distortion in the long-QT syndrome (Publications)
BACKGROUND: Congenital long-QT syndrome is a disorder resulting in ventricular arrhythmias and sudden death. The most common forms of the long-QT syndrome, types 1 and 2, are caused by mutations in th
Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of <em>Plasmodium falciparum</em> enoyl-ACP-reductase... (Publications)
Malaria, a disease of worldwide significance, is responsible for over one million deaths annually. The liver-stage of Plasmodium's life cycle is the first, obligatory, but clinically silent step in ma
Reproducibility of oscillometrically measured arterial stiffness indices: results of the SAPALDIA 3 cohort study (Publications)
Background. There is an increasing interest in oscillometric arterial stiffness measurement for cardiovascular risk stratification. We assessed reproducibility of the cuff-based arterial stiffness mea
Is there a differential impact of parity on blood pressure by age? (Publications)
OBJECTIVE: In pregnancy, women experience metabolic and hemodynamic changes of potential long-term impact. Conflicting evidence exists on the impact on blood pressure (BP). We investigated the associa
Rhinitis in Swiss adults is associated with asthma and early life factors, but not second hand tobacco smoke or obesity (Publications)
BACKGROUND: Second hand tobacco smoke (SHS) and overweight/obesity are risk factors for asthma and lower airway respiratory symptoms. We investigated whether SHS or overweight/obesity were also associ
Early life origins of lung ageing: early life exposures and lung function decline in adulthood in two European cohorts aged 28-73 years (Publications)
OBJECTIVES: Early life environment is essential for lung growth and maximally attained lung function. Whether early life exposures impact on lung function decline in adulthood, an indicator of lung ag
Long-term air pollution exposure and diabetes in a population-based Swiss cohort (Publications)
Air pollution is an important risk factor for global burden of disease. There has been recent interest in its possible role in the etiology of diabetes mellitus. Experimental evidence is suggestive, b