HMOX1 and GST variants modify attenuation of FEF25-75% decline due to PM10 reduction (Publications)
Reduced exposure to particulate matter with a 50% cut-off aerodynamic diameter of 10 microm (PM(10)) attenuated age-related lung function decline in our cohort, particularly in the small airways. We h
Spatial variation of PM elemental compositon between and within 20 European study areas - results of the ESCAPE project (Publications)
An increasing number of epidemiological studies suggest that adverse health effects of air pollution may be related to particulate matter (PM) composition, particularly trace metals. However, we lack
Air pollution and diabetes association: modification by type 2 diabetes genetic risk score (Publications)
Exposure to ambient air pollution (AP) exposure has been linked to type 2 diabetes (T2D) risk. Evidence on the impact of T2D genetic variants on AP susceptibility is lacking. Compared to single varian
Association between ambient air pollution and diabetes mellitus in Europe and North America: systematic review and meta-analysis (Publications)
BACKGROUND: Air pollution is hypothesized to be a risk factor for diabetes. Epidemiological evidence is inconsistent and has not been systematically evaluated. OBJECTIVES: We systematically reviewed e
Air pollution and atherosclerosis: a cross-sectional analysis of four European cohort studies in the ESCAPE study (Publications)
BACKGROUND: In four European cohorts, we investigated the cross-sectional association between long-term exposure to air pollution and intima-media thickness of the common carotid artery (CIMT), a pre-
Assessing seasonal variations and age patterns in mortality during the first year of life in Tanzania (Publications)
Lack of birth and death registries in most of developing countries, particularly those in sub-Saharan Africa led to the establishment of Demographic Surveillance Systems (DSS) sites which monitor larg
International workshop on insecticide resistance in vectors of arboviruses, December 2016, Rio de Janeiro, Brazil (Publications)
Vector-borne diseases transmitted by insect vectors such as mosquitoes occur in over 100 countries and affect almost half of the world's population. Dengue is currently the most prevalent arboviral di
Occurrence of and risk factors for <em>Strongyloides stercoralis</em> infection in South-East Asia (Publications)
The soil-transmitted nematode, Strongyloides stercoralis is one of the most-neglected of all neglected tropical diseases. It is globally distributed, favouring the humid, wet climates of the tropics a
The macrolide toxin mycolactone promotes bim-dependent apoptosis in Buruli ulcer through inhibition of mTOR (Publications)
Mycolactone, the macrolide exotoxin produced by Mycobacterium ulcerans, is central to the pathogenesis of the chronic necrotizing skin disease Buruli ulcer (BU). Here we show that mycolactone acts as
Modelling the health and economic impacts of the elimination of river blindness (onchocerciasis) in Africa (Publications)
BACKGROUND: Onchocerciasis (river blindness) is endemic mostly in remote and rural areas in sub-Saharan Africa. The treatment goal for onchocerciasis has shifted from control to elimination in Africa.