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1. Oral fexinidazole for stage 1 or early stage 2 African <em>Trypanosoma brucei gambiense</em> trypanosomiasis: a prospective, multicentre, open-label,... (Publications)

   Oral fexinidazole for stage 1 or early stage 2 African <em>Trypanosoma brucei gambiense</em> trypanosomiasis: a prospective, multicentre, open-label, cohort study

   Relevance:

   the safety and efficacy of fexinidazole in early g-HAT. METHODS: In this prospective, multicentre, open-label, single-arm cohort study, patients with stage 1 or early stage 2 g-HAT were recruited from eight

2. Efficacy and safety of intravenous ferric carboxymaltose compared with oral iron for the treatment of iron deficiency anaemia in women after... (Publications)

   Efficacy and safety of intravenous ferric carboxymaltose compared with oral iron for the treatment of iron deficiency anaemia in women after childbirth in Tanzania: a parallelgroup, open-label, randomised controlled phase 3 trial

   Relevance:

   following childbirth in women with iron deficiency anaemia in Tanzania. Methods: This parallel-group, open-label, randomised controlled phase 3 trial was done at Bagamoyo District Hospital and Mwananyamala

3. Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and... (Publications)

   Genotype-Informed Versus Empiric Management Of VirEmia (GIVE MOVE): study protocol of an open-label randomised clinical trial in children and adolescents living with HIV in Lesotho and Tanzania

   Relevance:

   an unsuppressed viral load (VL) while taking antiretroviral therapy (ART). METHODS: GIVE MOVE is an open-label randomised clinical trial enrolling children and adolescents (> /=6 months to /=400 copies/mL

4. Efficacy, safety and acceptability of a new chewable formulationversusthe solid tablet of mebendazole against hookworm infections in children: an... (Publications)

   Efficacy, safety and acceptability of a new chewable formulationversusthe solid tablet of mebendazole against hookworm infections in children: an open-label, randomized controlled trial

   Relevance:

   Background

5. Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized... (Publications)

   Switch to second-line versus continued first-line antiretroviral therapy for patients with low-level HIV-1 viremia: an open-label randomized controlled trial in Lesotho

   Relevance:

   benefit from a switch to second-line treatment. METHODS AND FINDINGS: This multicenter, parallel-group, open-label, superiority, randomized controlled trial enrolled patients on first-line ART containing no

6. Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster... (Publications)

   Efficacy of pragmatic same-day ring prophylaxis for adult individuals exposed to SARS-CoV-2 in Switzerland (COPEP): protocol of an open-label cluster randomised trial

   Relevance:

   INTRODUCTION

7. "When people get open about HIV, it's easier to save others" : Herausforderungen und Lösungswege in der HIV-Primärprävention von Aids-Versorgung bei... (Publications)

   "When people get open about HIV, it's easier to save others" : Herausforderungen und Lösungswege in der HIV-Primärprävention von Aids-Versorgung bei Sub-Sahara Migrationsgemeinschaften in der Schweiz

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8. Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis... (Publications)

   Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with <em>Opisthorchis viverrini</em>: a randomised, exploratory, open-label, phase 2 trial

   Relevance:

   compared with that of praziquantel in patients with O viverrini infection. METHODS: We did a randomised open-label trial between February and April, 2010, in the Saysetha district, Attapeu Province, Laos. Eligible

9. Fixed-dose artesunate-amodiaquine combination vs chloroquine for treatment of uncomplicated blood stage <em>P. vivax</em> infection in the Brazilian... (Publications)

   Fixed-dose artesunate-amodiaquine combination vs chloroquine for treatment of uncomplicated blood stage <em>P. vivax</em> infection in the Brazilian Amazon: an open-label randomized, controlled trial

   Relevance:

   BACKGROUND: Despite increasing evidence of the development of Plasmodium vivax chloroquine (CQ) resistance, there have been no trials comparing its efficacy with that of artemisinin-based combination

10. SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on... (Publications)

    SESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, r

    Relevance:

    second-line ART in patients with sustained unsuppressed VL. METHODS: In this multicenter, parallel-group, open-label, randomized controlled trial conducted in Lesotho, patients on first-line ART with two consecutive