Determination of optimal diagnostic cut-offs for the Naval Medical Research Centre scrub typhus IgM ELISA in Chiang Rai, Thailand (Publications)
In this diagnostic accuracy study, we evaluated data from 135 febrile patients from Chiang Rai, to determine the optimal optical density (OD) cutoffs for an in-house scrub typhus IgM ELISA. Receiver o
Pharmacokinetics of ascending doses of ivermectin in <em>Trichuris trichiura</em>-infected children aged 2-12 years (Publications)
BACKGROUND: Yearly, millions of children are treated globally with ivermectin mainly for neglected tropical diseases. Anatomical, physiological and biochemical differences between children and adults
Modeling the impact of sterile males on an <em>Aedes aegypti</em> population with optimal control (Publications)
We use partial differential equations to describe the dynamics of an Aedes aegypti mosquito population on an island, and the effects of a sterile male release. The model includes mosquito movement and
Is <em>Opisthorchis viverrini</em> emerging in Cambodia? (Publications)
Opisthorchis viverrini infection is widely prevalent in Southeast Asia. In Cambodia information on this helminth infection is scare. Recent reports suggest that O. viverrini is an emerging public heal
Clinical characteristics and outcome of children hospitalized with scrub typhus in an area of endemicity (Publications)
BACKGROUND: Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS: We recruited 60 febrile pediatric patients with a posit
Synthesis and biological investigation of (+)-3-hydroxymethylartemisinin (Publications)
Herein, we describe a biomimetic entry to (+)-3-hydroxymethylartemisinin (2) as well as to the artemisinin derivatives (+)-3-hydroxymethyl-9-desmethylartemisinin (16) and (+)-3-hydroxymethyl-9-epi-art
Exposure to moderate air pollution and associations with lung function at school-age: a birth cohort study (Publications)
BACKGROUND: Adverse effects of higher air pollution levels before and after birth on subsequent lung function are often reported in the literature. We assessed whether low-to-moderate levels of air po
Depression and anxiety symptoms in cardiac patients: a cross-sectional hospital-based study in a Palestinian population (Publications)
BACKGROUND: Mental health problems have an adverse effect on the course of cardiac disease. The integration of their diagnosis and treatment into cardiology care is generally poor. It is particularly
Molecular characterization and distribution of <em>Schistosoma</em> cercariae collected from naturally infected bulinid snails in northern and central... (Publications)
BACKGROUND: Accurate identification of schistosome species infecting intermediate host snails is important for understanding parasite transmission, schistosomiasis control and elimination. Cercariae e
Hospital outbreak due to <em>Clostridium difficile</em> ribotype 018 (RT018) in Southern Germany (Publications)
Clostridium (Clostridioides) difficile is the main cause of nosocomial diarrhoea. Ribotype 018 (RT018) has been recognized as the predominant strain responsible for C. difficile infection (CDI) in Ita