Public health impacts of city policies to reduce climate change: findings from the URGENCHE EU-China project (Publications)
BACKGROUND: Climate change is a global threat to health and wellbeing. Here we provide findings of an international research project investigating the health and wellbeing impacts of policies to reduc
Identification of new human malaria parasite <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase inhibitors by pharmacophore and... (Publications)
Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH), a key enzyme in the de novo pyrimidine biosynthesis pathway, which the Plasmodium falciparum relies on exclusively for survival, has emerg
Bimodal X-ray and infrared imaging of an organometallic derivative of praziquantel in <em>Schistosoma mansoni</em> (Publications)
An organometallic derivative of praziquantel was studied directly in worms, using ICP-MS for quantification and synchrotron based imaging. X-Ray fluorescence and IR absorption microspectroscopy, were
Reaching the surveillance-response stage of schistosomiasis control in the People's Republic of China: a modelling approach (Publications)
With the goal set to eliminate schistosomiasis nationwide by 2020, The People's Republic of China has initiated the surveillance-response stage to identify remaining sources of infection and potential
Synthesis of novel amide and urea derivatives of thiszol-2-ethylamines and their activity against<em> Trypanosoma brucei rhodesiense</em> (Publications)
2-(2-Benzamido)ethyl-4-phenylthiazole (1) was one of 1035 molecules (grouped into 115 distinct scaffolds) found to be inhibitory to Trypanosoma brucei, the pathogen causing human African trypanosomias
Health-related quality of life and its association with medication adherence in active pulmonary tuberculosis- a systematic review of global... (Publications)
INTRODUCTION: Tuberculosis (TB) is a leading cause of morbidity and mortality in South Africa. Clinical parameters are important objective outcomes in TB; however they often are not directly correlate
Direct susceptibility testing of <em>Mycobacterium tuberculosis</em> for pyrazinamide using the BACTEC MGIT 960 system (Publications)
Pyrazinamide is a key antituberculosis drug, yet no rapid susceptibility test is commercially available. PZA drug susceptibility testing (DST) was performed directly on the sputum from 327 patients an
Vitamin-D status is not a confounder of the relationship between zinc and diarrhoea: a study in 6-24-month-old underweight and normal-weight children... (Publications)
BACKGROUND/OBJECTIVE: The role of micronutrients particularly zinc in childhood diarrhoea is well established. Immunomodulatory functions of vitamin-D in diarrhoea and its role in the effect of other
Molecular biogeography of red deer Cervus elaphus from eastern Europe: insights from mitochondrial DNA sequences (Publications)
European red deer are known to show a conspicuous phylogeographic pattern with three distinct mtDNA lineages (western, eastern and North-African/Sardinian). The western lineage, believed to be indicat