Searched for malaria.

1. Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria (Publications)

   Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

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   it was shown to be safe at doses up to 1,600 mg and is currently undergoing Phase IIa trials in malaria patients. Herein, we describe the discovery of OZ439 and the exceptional antimalarial and pharmacokinetic

2. A periodically-forced mathematical model for the seasonal dynamics of malaria in mosquitoes (Publications)

   A periodically-forced mathematical model for the seasonal dynamics of malaria in mosquitoes

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   orbits of field-measurable quantities that measure malaria transmission. We integrate this model with an individual-based stochastic simulation model for malaria in humans to compare the effects of insectic [...] interventions reduce transmission and prevalence, they can lead to increased clinical malaria; and all three malaria indicators return to preintervention levels within 3 years after the interventions are [...] We describe and analyze a periodically-forced difference equation model for m...

3. Developmental impairments following severe falciparum malaria in children (Publications)

   Developmental impairments following severe falciparum malaria in children

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   complications of falciparum malaria, such as multiple, prolonged or focal seizures, is not known. Thus, our objective was to investigate the long-term developmental outcome of CM and malaria with complicated seizures [...] OBJECTIVE: Neurological deficits are reported in children after cerebral malaria (CM) but little is known about the prevalence and characteristics of persisting neurocognitive consequences. The prevalence [...] y increases the risk of cognitive and behavioural problems in...

4. Density independent feeding success of malaria vectors (Diptera: Culicidae) in Tanzania (Publications)

   Density independent feeding success of malaria vectors (Diptera: Culicidae) in Tanzania

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5. A hopeful beginning for malaria vaccines (Publications)

   A hopeful beginning for malaria vaccines

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6. Integrated urban malaria control: a case study in Dar es Salaam, Tanzania (Publications)

   Integrated urban malaria control: a case study in Dar es Salaam, Tanzania

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7. Modeling the relationship between the population prevalence of <em>Plasmodium falciparum</em> malaria and anemia (Publications)

   Modeling the relationship between the population prevalence of <em>Plasmodium falciparum</em> malaria and anemia

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8. Development of influenza virosome-based synthetic malaria vaccines (Publications)

   Development of influenza virosome-based synthetic malaria vaccines

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9. Clinical and laboratory predictors of imported malaria in an outpatient setting: an aid to medical decision making in returning travelers with fever (Publications)

   Clinical and laboratory predictors of imported malaria in an outpatient setting: an aid to medical decision making in returning travelers with fever

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   had the highest positive likelihood ratio for a diagnosis of malaria (13.6), followed by thrombopenia (11.0). Posttest probabilities for malaria were 85% with enlarged spleen and 82% with thrombopenia. A [...] information exists to guide clinicians for giving presumptive treatment to returning travelers when malaria is strongly suspected on clinical grounds but laboratory confirmation is not immediately available [...] laboratory predictors of Plasmodium parasitemia. A total of 336...

10. Adhesion of <em>Plasmodium falciparum</em>-infected red blood cells to CD36 under flow is enhanced by the cerebral malaria-protective trait South-East... (Publications)

    Adhesion of <em>Plasmodium falciparum</em>-infected red blood cells to CD36 under flow is enhanced by the cerebral malaria-protective trait South-East Asian ovalocytosis

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