Human T cell epitopes of <em>Mycobacterium tuberculosis</em> are evolutionarily hyperconserved (Publications)
Mycobacterium tuberculosis is an obligate human pathogen capable of persisting in individual hosts for decades. We sequenced the genomes of 21 strains representative of the global diversity and six ma
A role for systems epidemiology in tuberculosis research (Publications)
Despite being a curable disease, tuberculosis (TB) killed more people in 2009 than during any previous year in history. Progress in TB research has been slow, and remains burdened by important gaps in
Oral treatment for <em>Mycobacterium ulcerans</em> infection: results from a pilot study in Benin (Publications)
Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chem
Incidence of asthma and net change in symptoms in relation to changes in obesity (Publications)
The incidence of asthma has been reported to be associated with obesity. An alternative analysis, of net change in prevalence, does not require exclusion of those with asthma at baseline.Follow-up dat
Honeys from different floral sources as inhibitors of enzymatic browning in fruit and vegetable homogenates (Publications)
Honeys from different floral sources were evaluated for their antioxidant content and for their ability to inhibit enzymatic browning in fruits and vegetables. Antioxidant contents of honeys vary wide
Modelling vertical transmission in vector-borne diseases with applications to Rift Valley fever (Publications)
We present two ordinary differential equation models for Rift Valley fever (RVF) transmission in cattle and mosquitoes. We extend existing models for vector-borne diseases to include an asymptomatic h
Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents (Publications)
We report herein the synthesis and trypanocidal profile of new (E)-cinnamic N-acylhydrazones (NAHs) designed by exploiting molecular hybridization between the potent cruzain inhibitors (E)-1-(benzo[d]
Cost-effectiveness of invasive versus medical management of elderly patients with chronic symptomatic coronary artery disease. Findings of the... (Publications)
AIM: To compare benefits and costs of invasive versus medical management in elderly patients with chronic angina. METHODS AND RESULTS: In a predefined subgroup of 188 patients of the Trial of Invasive
