Searched for malaria.

1. Operational strategies to achieve and maintain malaria elimination (Publications)

   Operational strategies to achieve and maintain malaria elimination

   Relevance:

   Present elimination strategies are based on recommendations derived during the Global Malaria Eradication Program of the 1960s. However, many countries considering elimination nowadays have high intrinsic [...] need to revisit the strategies on which contemporary elimination programmes are based. To eliminate malaria, programmes need to concentrate on identification and elimination of foci of infections through both [...] of infectious pools entirely will not be sufficient since they could be...

2. Force of infection is key to understanding the epidemiology of <em>Plasmodium falciparum</em> malaria in Papua New Guinean children (Publications)

   Force of infection is key to understanding the epidemiology of <em>Plasmodium falciparum</em> malaria in Papua New Guinean children

   Relevance:

   describes basic malaria epidemiology and is suitable for measuring outcomes of interventions. This study was designed to test whether (mol)FOI influenced the risk of clinical malaria episodes and how [...] highlights the suitability of (mol)FOI as a measure of individual exposure and its central role in malaria epidemiology. It has substantial advantages over entomological measures in studies of transmission

3. Vaccines against malaria: perspectives from Papua New Guinea (Publications)

   Vaccines against malaria: perspectives from Papua New Guinea

   Relevance:

   perspectives on malaria vaccines. Building on a long history of malaria research, in this article we review past achievements, highlight current research and outline future directions in malaria vaccine research [...] transmission of all four species of human malaria, a full range of malaria endemicities, well described epidemiology and a demonstrated capacity to evaluate a malaria vaccine, PNG currently has the only field [...] Despite its small population and isolated location Papua New Guinea...

4. Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya (Publications)

   Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya

   Relevance:

   Background. Clear case definitions of malaria are an essential means of evaluating the effectiveness of present and proposed interventions in malaria. The clinical signs of malaria are nonspecific, and parasitemia [...] episode of clinical malaria in endemic areas. We defined and quantified cases of malaria in people of different age groups from 2 areas with different rates of transmission of malaria.Methods. A total of [...] of malaria.Results. Two case definitions of malaria were derived: 1...

5. The straw that breaks the camel's back: redirecting health-seeking behavior studies on malaria and vulnerability (Publications)

   The straw that breaks the camel's back: redirecting health-seeking behavior studies on malaria and vulnerability

   Relevance:

   Development Goals, the focus on vulnerability and access to care has increasingly gained ground in the malaria social science literature. However, little emphasis has been given to the cumulative processes of

6. The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor... (Publications)

   The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor treatment outcomes in an area of Papua New Guinea in which malaria is endemic

   Relevance:

   Using in vivo samples from treatment failure malaria cases, we demonstrate the high sensitivity of the parasite lactase dehydrogenase (pLDH)-based OptiMAL rapid diagnostic test in the detection of P.

7. <em>In vitro</em> screening of traditional South African malaria remedies against <em>Trypanosoma brucei rhodesiense</em>, <em>Trypanosoma cruzi,... (Publications)

   <em>In vitro</em> screening of traditional South African malaria remedies against <em>Trypanosoma brucei rhodesiense</em>, <em>Trypanosoma cruzi, Leishmania donovani,</em> and <em>Plasmodium falciparum</em>

   Relevance:

   Three hundred extracts were prepared from plants traditionally used in South Africa to treat malaria and screened IN VITRO for activity against TRYPANOSOMA BRUCEI RHODESIENSE, TRYPANOSOMA CRUZI, LEISHMANIA

8. Analysis of <em>Plasmodium falciparum</em> var gene repertoire expressed in childrenwith severe malaria from Tanzania (Publications)

   Analysis of <em>Plasmodium falciparum</em> var gene repertoire expressed in childrenwith severe malaria from Tanzania

   Relevance:

9. Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation (Publications)

   Structure-activity-based design of a synthetic malaria peptide eliciting sporozoite inhibitory antibodies in a virosomal formulation

   Relevance:

   ozoite protein (CSP) of Plasmodium falciparum is a leading candidate antigen for inclusion in a malaria subunit vaccine. We describe here the design of a conformationally constrained synthetic peptide

10. Does radical cure of asymptomatic <em>Plasmodium falciparum</em> place adults in endemic areas at increased risk of recurrent symptomatic malaria? (Publications)

    Does radical cure of asymptomatic <em>Plasmodium falciparum</em> place adults in endemic areas at increased risk of recurrent symptomatic malaria?

    Relevance:

    District (northern Ghana) was radically cured of malaria parasites to study subsequent incidence of malaria infection. During the following 20 weeks of the malaria transmission season, 49% experienced clinical [...] hypothesis that radical cure of P. falciparum enhances the risk and severity of subsequent clinical malaria attacks.