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1. Efficacy and safety of artesunate plus amodiaquine and artemether plus lumefantrine in the treatment of uncomplicated <em>Plasmodium falciparum</em>... (Publications)

   Efficacy and safety of artesunate plus amodiaquine and artemether plus lumefantrine in the treatment of uncomplicated <em>Plasmodium falciparum</em> malaria in the Democratic Republic of Congo: an open-label randomized trial

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2. Managing research and surveillance projects in real-time using a novel open-source eManagement tool designed for low-resourced countries (Publications)

   Managing research and surveillance projects in real-time using a novel open-source eManagement tool designed for low-resourced countries

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3. Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against <em>Schistosoma haematobium</em>: a randomized, exploratory,... (Publications)

   Praziquantel, mefloquine-praziquantel, and mefloquine-artesunate-praziquantel against <em>Schistosoma haematobium</em>: a randomized, exploratory, open-label trial

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   BACKGROUND: Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel. Hence, there is a pressing need to develop additional therapeutics against schistosomiasis. The an

4. Open randomized trial in hepatitis B non- and low-responders to compare the immunogenicity and safety of a recombinant third-generation Pre-S1/S2... (Publications)

   Open randomized trial in hepatitis B non- and low-responders to compare the immunogenicity and safety of a recombinant third-generation Pre-S1/S2 hepatitis B vaccine and a standard hepatitis B vaccine

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5. Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial (Publications)

   Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial

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   efficacy of a local heat application device based on phase change material. METHODS: In a phase II open label single center non comparative clinical trial (ISRCTN 72102977) under GCP standards in Cameroon

6. Open Malaria : a simulator program for studying malaria epidemiology and the impacts of interventions against malaria [Software] (Publications)

   Open Malaria : a simulator program for studying malaria epidemiology and the impacts of interventions against malaria [Software]

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   OpenMalaria is an open source C++ program for simulating malaria epidemiology and the impacts on that epidemiology of interventions against malaria. It is based on microsimulations of

7. Fixed-dose artesunate-amodiaquine combination vs chloroquine for treatment of uncomplicated blood stage <em>P. vivax</em> infection in the Brazilian... (Publications)

   Fixed-dose artesunate-amodiaquine combination vs chloroquine for treatment of uncomplicated blood stage <em>P. vivax</em> infection in the Brazilian Amazon: an open-label randomized, controlled trial

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   BACKGROUND: Despite increasing evidence of the development of Plasmodium vivax chloroquine (CQ) resistance, there have been no trials comparing its efficacy with that of artemisinin-based combination

8. Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label... (Publications)

   Tribendimidine and albendazole for treating soil-transmitted helminths, <em>Strongyloides stercoralis</em> and <em>Taenia</em> spp.: open-label randomized trial

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   point to activity against cestodes and Strongyloides ratti. METHODOLOGY/PRINCIPAL FINDINGS: In an open-label randomized trial, the safety and efficacy of a single oral dose of albendazole or tribendimidine

9. Eleven-year single-center experience with the ATS Open Pivot Bileaflet heart valve (Publications)

   Eleven-year single-center experience with the ATS Open Pivot Bileaflet heart valve

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   BACKGROUND: The ATS Open Pivot Heart Valve was first introduced in 1992 and has been implanted routinely at our institution since 1993. Valve selection was based on surgeon preference. The objective of [...] 11-year experience demonstrates low rates of adverse events and valve-related complications with the ATS Open Pivot heart valve

10. A multicenter, open label, phase III study of therapeutic use of the co-administration of nifurtimox and eflornithine (NECT) for human African... (Publications)

    A multicenter, open label, phase III study of therapeutic use of the co-administration of nifurtimox and eflornithine (NECT) for human African trypanosomiasis (NECT field): safety profile in children during initial hospitalization

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