<em>Plasmodium falciparum</em> cerebral malaria complicated by disseminated intravascular coagulation and symmetrical peripheral gangrene: case report... (Publications)
The case of a 56-year-old female tourist who survived cerebral Plasmodium falciparum malaria with disseminated intravascular coagulation and symmetrical peripheral gangrene, ultimately requiring amputation [...] gangrene has been described rarely in Asian, African, and American patients with Plasmodium falciparum malaria and disseminated intravascular coagulation, no such case has been reported in travelers returning
An estimation of the entomological inoculation rate for Ifakara: a semi-urban area in a region of intense malaria transmission in Tanzania (Publications)
An entomological study on vectors of malaria and their relative contribution to Plasmodium falciparum transmission in the semi-urban area of Ifakara, south-eastern Tanzania, was conducted. A total of 32
Passive immunoprotection of <em>Plasmodium falciparum</em>-infected mice designates the CyRPA as candidate malaria vaccine antigen (Publications)
An effective malaria vaccine could prove to be the most cost-effective and efficacious means of preventing severe disease and death from malaria. In an endeavor to identify novel vaccine targets, we tested [...] represents an unprecedented in vivo model for quantitative comparison of the functional potencies of malaria-specific Abs. Our data suggest a role for CyRPA in erythrocyte invasion by the merozoite. Inhibition [...] merozoite invasion by CyRPA-specific mAbs in vitro and in vivo renders...
Effect of the malaria vaccine combination B on merozoite surface antigen 2 diversity (Publications)
Plasmodium falciparum surface antigens. This poses a considerable obstacle to the development of a malaria vaccine. In order to assess possible effects of a polymorphic vaccine, we have analyzed the genetic
Evaluation of two long synthetic merozoite surface protein 2 peptides as malaria vaccine candidates (Publications)
peptide-specific antibodies in human immune sera were associated with protection from clinical malaria. The synthetic fragments share major antigenic properties with native MSP2. Immunization of mice