Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease (Publications)
The integrity of the inner membrane of mitochondria is maintained by a membrane-embedded quality control system that ensures the removal of misfolded membrane proteins. Two ATP-dependent AAA proteases
Structural requirements of Tom40 for assembly into preexisting TOM complexes of mitochondria (Publications)
Tom40 is the major subunit of the translocase of the outer mitochondrial membrane (the TOM complex). To study the assembly pathway of Tom40, we have followed the integration of the protein into the TO
Differential gene repertoire in <em>Mycobacterium ulcerans</em> identifies candidate genes for patho-adaptation (Publications)
BACKGROUND: Based on large genomic sequence polymorphisms, several haplotypes belonging to two major lineages of the human pathogen Mycobacterium ulcerans could be distinguished among patient isolates
Analysis of the <em>Mycobacterium ulcerans</em> genome sequence reveals new loci for variable number tandem repeats (VNTR) typing (Publications)
Screening of the genome sequence of the Mycobacterium ulcerans strain Agy99 from Ghana with tandem repeats finder software revealed 34 novel non-degenerate tandem repeats containing loci suitable for
Protein degradation in mitochondria (Publications)
The biogenesis of mitochondria and the maintenance of mitochondrial functions depends on an autonomous proteolytic system in the organelle which is highly conserved throughout evolution. Components of
