Quantifying the impact of interventions against <em>Plasmodium vivax</em>: a model for country-specific use (Publications)
fictitious data, by simulating and comparing the impact of various intervention combinations on malaria risk and burden, this model could be a useful tool for strategic planning, implementation and resource
Activities (Page)
https://www.swisstph.ch/en/about/events/open-house-2023/activities
Swiss TPH: A Glimpse into the Past Clinical Research: Bringing a Drug to Market** Healthy Travel: Malaria, Rabies and Yellow Fever Stuffed Animal Hospital: Making Your Furry Friend Healthy Again* 1 st floor [...] Digital Health for Early Childhood Development Disease Detectives: Investigating an Outbreak** Malaria Maze: Navigating the Impenetrable Mosquito Net*/** From the Wild to Paper: Comic Creation with Fizzi**
Modified mosquito landing boxes dispensing transfluthrin provide effective protection against <em>Anopheles arabiensis</em> mosquitoes under simulated... (Publications)
BACKGROUND: Efforts to control malaria vectors have primarily focused on scaling-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying. Although highly efficient against indoor-biting [...] outdoor-biting mosquitoes in the peri-domestic space. They have a potential role in combatting outdoor malaria transmission without interfering with effective indoor interventions such as LLINs
Identification of oleamide in <em>Guatteria</em> recurvisepala by LC/MS-Based <em>Plasmodium falciparum</em> thioredoxin reductase ligand binding... (Publications)
current research on applications of mass spectrometry to natural product drug discovery against malaria aims to screen plant extracts for new ligands to PLASMODIUM FALCIPARUM thioredoxin reductase ( PFTrxR) [...] regulation of the parasite and is validated as a promising target for therapeutic intervention against malaria. In the present study, detannified methanol extracts from GUATTERIA RECURVISEPALA, LICANIA KALLUNKIAE
A 39-amino-acid C-terminal truncation of GDV1 disrupts sexual commitment in<em> Plasmodium falciparum</em> (Publications)
Malaria is a mosquito-borne disease caused by apicomplexan parasites of the genus Plasmodium. Completion of the parasite's life cycle depends on the transmission of sexual stages, the gametocytes, from [...] important to sustain GDV1 protein levels and thereby sexual commitment.IMPORTANCE Transmission of malaria-causing Plasmodium species by mosquitos requires the parasite to change from a continuously growing
Attributes of <em>Anopheles gambiae</em> swarms in South Central Uganda (Publications)
BACKGROUND: Anopheles gambiae continues to be widespread and an important malaria vector species complex in Uganda. New approaches to malaria vector control are being explored including population suppression
New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities (Publications)
of sleeping sickness, Trypanosoma brucei rhodesiense, as well as against a causative organism of malaria, Plasmodium falciparum NF54. Their cytotoxic properties were determined with L-6 cells (rat skeletal
Discovery and structure-activity relationships of pyrrolone antimalarials (Publications)
2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways
Christian Selinger (People)
https://www.swisstph.ch/en/staff/profile/people/christian-selinger
in pathogens and diseases affecting humans such as HIV, Influenza, Polio, HPV, Coronaviruses and Malaria.
Aurélie Jeandron (People)
https://www.swisstph.ch/en/staff/profile/people/aurelie-jeandron
operational challenges posed by resource-limited settings. She recently broadened her expertise to malaria modelling, after having focused on water, sanitation and hygiene and environmental health. Education