Predictive value of clinical and laboratory features for the main febrile diseases in children living in Tanzania: a prospective observational study (Publications)
also found: malaria could be ruled in by recent travel, typhoid by jaundice, radiological pneumonia by very fast breathing and UTI by fever duration of > /=4 days. The CART model for malaria included t
Expression of the MSPDBL2 antigen in a discrete subset of <em>Plasmodium falciparum</em> schizonts is regulated by GDV1 but may not be linked to... (Publications)
requires further investigation in natural infections where it is under immune selection. IMPORTANCE: Malaria parasites in the blood are remarkably variable, able to switch antigenic targets so they may survive [...] developed specific immune responses. This is one of the challenges in developing vaccines against malaria. MSPDBL2 is a target of naturally acquired immunity expressed in minority proportions of schizonts
Biostatistics | Research at Swiss TPH (Page)
https://www.swisstph.ch/en/about/eph/biostatistics
fields of epidemiology, parasitology and infection biology. Primary areas of applications involve malaria, anaemia, neglected diseases, HIV, mortality, cancer and environmental epidemiology. Research is [...] and stakeholders' analysis Estimating the extent, patterns and consequences of heterogeneity in malaria dynamics EBF - Exclusive breastfeeding: global rates, optimal duration, and a multi-country intervention [...] Evaluations Services Related Topics Environment and Health Health...
10 Years Swiss TPH: Integration of the ISPM into the Former Swiss Tropical Institute (News)
https://www.swisstph.ch/en/news/news-detail/news/10-years-swiss-tph-integration-of-the-ispm-into-the-former-swiss-tropical-institute
one roof. STI was especially strong in the areas of research in poverty-related diseases, such as malaria and sleeping sickness, as well as healthcare system research in African countries. ISPM was known [...] this important? Nino Künzli: “There is still a risk of traditional infectious diseases, such as malaria, tuberculosis and HIV/AIDS, but thanks to successful research, these infectious diseases can be treated [...] unhealthy combination. In addition, there has been little research, for...
Media Releases (Page)
https://www.swisstph.ch/en/about/dir/communications/media-releases
01.04.2022 New Swiss TPH Headquarters Opened in Allschwil 03.02.2022 Analysis of 20 Years Finds Malaria Control in Young Children Saves Lives into Adulthood 02.02.2022 The Swiss TPH Travel Clinic Temporarily
A Programmatic Analysis of integrated Community Case Management (iCCM): A Multicountry Systems-Wide Analysis of the RAcE (Rapid Access Expansion) iCCM... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/a-programmatic-analysis-of-integrated-community-case-management-iccm-a-multicountry-systems-wide-analysis-of-the-race-rapid-access-expansion-iccm-programme-in-sub-saharan-africa
provide children living in remote areas with access to case management for pneumonia, diarrhea, and malaria at the community level. The Rapid Access Expansion Programme (RAcE), steered by the World Health
Strategies for conducting <em>Anopheles stephensi </em>surveys in non-endemic areas (Publications)
Anopheles stephensi, a malaria vector species previously only known from Asia, was first detected in Africa in Djibouti in 2012, has been subsequently collected in Ethiopia, Sudan, and Somalia, and may
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate... (Publications)
DHODH inhibitors have great potential for use in prophylaxis, which represents an unmet need in the malaria drug discovery portfolio for endemic countries, particularly in areas of high transmission in Africa
Antimalarial benzoheterocyclic 4-aminoquinolines: structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies (Publications)
for antiplasmodial activity against K1 (multidrug resistant) and NF54 (sensitive) strains of the malaria parasite Plasmodium falciparum. Structure-activity relationship studies led to the identification
Decreased in vitro susceptibility of <em>Plasmodium falciparum</em> isolates to artesunate, mefloquine, chloroquine, and quinine in Cambodia from 2001... (Publications)
from patients enrolled in therapeutic efficacy studies (TES) conducted by the Cambodian National Malaria Control Program for the routine efficacy monitoring of artemisinin-based combination therapy (ACT)