Natural killer cell cytokine response to <em>M. bovis</em> BCG is associated with inhibited proliferation, increased apoptosis and ultimate depletion... (Publications)
Mycobacterium bovis BCG, a live attenuated strain of M. bovis initially developed as a vaccine against tuberculosis, is also used as an adjuvant for immunotherapy of cancers and for treatment of paras
A large <em>Plasmodium vivax</em> reservoir and little population structure in the South Pacific (Publications)
INTRODUCTION: The importance of Plasmodium vivax in malaria elimination is increasingly being recognized, yet little is known about its population size and population genetic structure in the South Pa
The cell wall-associated mycolactone polyketide synthases are necessary but not sufficient for mycolactone biosynthesis (Publications)
Mycolactones are polyketide-derived lipid virulence factors made by the slow-growing human pathogen, Mycobacterium ulcerans. Three unusually large and homologous plasmid-borne genes (mlsA1: 51 kb, mls
Quest for a potent antimalarial drug lead: synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines (Publications)
Quinazolines have long been known to exert varied pharmacologic activities that make them suitable for use in treating hypertension, viral infections, tumors, and malaria. Since 2014, we have synthesi