Epidemiology of multiple<em> Plasmodium falciparum </em>infections. 4. Age dependence of the multiplicy of <em>Plasmodium falciparum</em> infections... (Publications)
result, peak prevalence was reached in 3-5 years old children. However, the prevalence of clinical malaria (estimated from the excess risk of axillary temperatures > or = 37.5 degrees C attributable to p
The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes (Publications)
vaccine formulations, circulating Tfh cells were expanded in Tanzanian volunteers when an experimental malaria vaccine was adjuvanted in GLA-SE but not when formulated in Alum. The GLA-SE-formulated peptide was
Conformational aspects in the design of inhibitors for serine hydroxymethyltransferase (SHMT): biphenyl, aryl sulfonamide, and aryl sulfone motifs (Publications)
Malaria remains a major threat to mankind due to the perpetual emergence of resistance against marketed drugs. Twenty-one pyrazolopyran-based inhibitors bearing terminal biphenyl, aryl sulfonamide, or
Status of insecticide resistance in Papua New Guinea: an update from nation-wide monitoring of anopheles mosquitoes (Publications)
distribution of insecticide-treated nets. Here, we provide an update on phenotypic IR in four highly malaria-endemic areas of PNG. IR against deltamethrin, lambda-cyhalothrin, and dichlorodiphenyltrichloroethane
Swiss TPH Awarded Four New Research Grants in Paediatric Health (News)
https://www.swisstph.ch/en/news/news-detail/news/swiss-tph-awarded-four-new-research-grants-in-paediatric-health
al Nets to Maximise Universal Access Long-lasting insecticidal nets (LLINs) are the mainstay of malaria control. However, more than 50% of people living in endemic areas are currently unprotected because [...] Health Institute and the Ministry of Health in Tanzania will develop a digital tool enabling national malaria control programs to improve planning for programmatic LLIN distribution, monitoring of LLIN quality [...] mosquito net lifespan will optimise resource use, increase the protection...
Symposium Professorship in Neglected Tropical Diseases (News)
https://www.swisstph.ch/en/news/news-detail/news/symposium-professorship-in-neglected-tropical-diseases
Université de Fribourg Extracellular vesicles in the regulation of host-pathogen interactions during malaria 11:10 – 11:50 Dr. Catherine Ronet Université de Lausanne Leishmania-RNA virus subverts the host immune
Antimalarials in the treatment of schistosomiasis (Publications)
experiences made thus far from clinical studies. We conclude that a closer collaboration between the malaria and schistosomiasis communities might facilitate the discovery and development of novel antischistosomal
Ultrasonography of gallbladder abnormalities due to schistosomiasis (Publications)
After malaria, schistosomiasis remains the most important tropical parasitic disease in large parts of the world. Schistosomiasis has recently re-emerged in Southern Europe. Intestinal schistosomiasis
Evidence that <em>Plasmodium falciparum</em> chromosome end clusters are cross-linked by protein and are the sites of both virulence gene silencing... (Publications)
The malaria parasite Plasmodium falciparum undergoes antigenic variation through allelic exclusion and variant expression of surface proteins encoded by the var gene family. Regulation of var genes is
Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities (Publications)
the low micromolar to submicromolar range against Trypanosoma brucei rhodesiense as well as the malaria parasite Plasmodium falciparum