Scoping Study for a Strategic Environmental Assessment (SEASS) on the potential operational use of gene drive in the main malaria-carrying Anopheles... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/scoping-study-for-a-strategic-environmental-assessment-seass-on-the-potential-operational-use-of-gene-drive-in-the-main-malaria-carrying-anopheles-mosquito-species-in-west-africa-on-behalf-of-target-malaria
Target Malaria isa not-for-profit research consortium that aims to develop and share new, cost-effective, and sustainable genetic technologies to modify mosquitoes and reduce malaria transmission. The [...] The intervention which is currently in development by Target Malaria (i.e. a population suppression gene drive) works by reducing the ability of female mosquitoes to reproduce through non-mendelian inheritance [...] inheritance of an introduced gene targeting female fertility, thereby...
Assessment of the effect of larval source management and house improvement on malaria transmission when added to standard malaria control strategies... (Publications)
residual spraying (IRS) will be insufficient as stand-alone malaria vector control interventions in many settings as programmes shift toward malaria elimination. Combining additional vector control interventions [...] together with the interventions currently implemented by the Malawi National Malaria Control Programme is anticipated to reduce malaria transmission below the level reached by current interventions alone. I [...] We will implement community-based LSM and HI, as additional...
OpenMalaria Workflow and OpenMalariaUtilities R Packages (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/openmalaria-workflow-and-openmalariautilities-r-packages
Swiss TPH GitHub . OpenMalariaUtilities R Package At the core of our OpenMalaria Workflow is the OpenMalariaUtilities R package which is developed to allow the use of OpenMalaria directly from R. The package [...] OpenMalaria Workflow R Package The work of the Analytics and Intervention Modelling Group is based on OpenMalaria : an open-source C++ program for simulating malaria epidemiology and the impacts on that [...] TPH GitHub. The OpenMalaria Workflow R Package together with the OpenMalariaU...
Child Health and Infection with Low Density (CHILD) Malaria, a randomized controlled trial to assess the long-term health and socioeconomic impact of... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/child-health-and-infection-with-low-density-child-malaria-a-randomized-controlled-trial-to-assess-the-long-term-health-and-socioeconomic-impact-of-interventions-targeting-low-density-malaria-infection-lmi-among-children-in-tanzania
As malaria transmission declines, an increasing proportion of infections persist in the body at low levels. Low-density malaria infection (LMI) are often chronic and represent a high proportion of infections [...] they may provide protective immunity again future malaria illness. There is a growing body evidence to suggest that LMI are associated with recurrent malaria, chronic anemia, poor growth, co-infection with [...] for malaria (using RDT and qPCR) three times annually, with AL...
Science of Eradication: Malaria (Courses)
Eradication: Malaria Core Course is an intensive weeklong foundational leadership development course that provides participants with a multidisciplinary perspective on approaches to malaria elimination
Malaria eradication requires more than magic bullets (Blog)
https://www.swisstph.ch/en/impact-stories/malaria-eradication-requires-more-than-magic-bullets/blog-id/39
The global community has made impressive strides in malaria control and elimination, but progress has stalled. To reach eradication, we must rethink our approach.
There is no excuse for the world to still have malaria (Blog)
https://www.swisstph.ch/en/impact-stories/there-is-no-excuse-for-the-world-to-still-have-malaria/blog-id/13
years, much has been invested in malaria prevention and treatment, resulting in the prevention of over 7.6 million malaria deaths. The progress made in the fight against malaria is one of the greatest success [...] Mosquitoes infect millions of people with malaria - a disease that kills a child every two minutes. Most of these deaths occur in the poorest countries with the weakest health systems. Over the past 20
World Malaria Day 2021: In the shadows of the COVID-19 pandemic (Blog)
https://www.swisstph.ch/en/impact-stories/world-malaria-day-2021-in-the-shadows-of-the-covid-19-pandemic/blog-id/14
A world without malaria is within reach. At the same time, the COVID-19 pandemic threatens progress in the fight against malaria. This year's World Malaria Day on 25 April 2021 will draw attention to the [...] the fact that further efforts are needed to achieve the goal of a malaria-free world.
Malaria eradication requires more than magic bullets (Page)
https://www.swisstph.ch/en/impact-stories/malaria-eradication-requires-more-than-magic-bullets
From 2000-2021, 1.5 billion malaria cases and 7.6 million malaria deaths have been averted. This should be a strong motivator to up our collective game. The road ahead for malaria elimination was well summarized [...] However, malaria transmission remains intense and devastating in some parts of the world, particularly in sub-Saharan Africa. "Clearly, a change is required to reach the ultimate goal of malaria eradication [...] the impressive successes of malaria control from 2000-2015 in endemic...
