Atropo-enantioselective total synthesis of knipholone and related antiplasmodial phenylanthraquinones (Publications)
The "lactone concept" has been efficiently employed for the first atropo-enantioselective synthesis of knipholone and related natural phenylanthraquinones. Besides the regio- and stereoselective const
The National Schistosomiasis Control Programme in Mali: objectives, organization, results (Publications)
Schistosomiasis control started regionally, in the Bandiagara district, and as a component of a dam-building project in 1978. In 1982 a national programme was created. Control was divided into three p
Inhibitors of Plasmepsin II-potential antimalarial agents (Publications)
In order to overcome the problem of drug resistance in malaria, it appears wise to concentrate drug discovery efforts toward new structural classes and new mechanisms of action. We report our results,
Use of spoligotyping and large sequence polymorphisms to study the population structure of the <em>Mycobacterium tuberculosis</em> complex in a cohort... (Publications)
Mycobacterium africanum, first described in Senegal in 1968, causes up to half of the smear-positive pulmonary tuberculosis cases in West Africa, but it has not been found in other geographical areas
Progression to active tuberculosis, but not transmission, varies by <em>Mycobacterium tuberculosis</em> lineage in The Gambia (Publications)
BACKGROUND: There is considerable variability in the outcome of Mycobacterium tuberculosis infection. We hypothesized that Mycobacterium africanum was less likely than M. tuberculosis to transmit and
<em>Mycobacterium africanum</em> elicits an attenuated T cell response to early secreted antigenic target, 6 kDa, in patients with tuberculosis and... (Publications)
BACKGROUND: Mycobacterium africanum, a member of the M. tuberculosis complex that is infrequently found outside of western Africa, is the cause of up to half of the tuberculosis cases there. METHODS:
