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1. Availability and satisfactoriness of latrines and hand washing stations in health facilities, and role in health seeking behavior of women: evidence... (Publications)

   Availability and satisfactoriness of latrines and hand washing stations in health facilities, and role in health seeking behavior of women: evidence from rural Pune district, India

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2. The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity (Publications)

   The lipid-modifying enzyme SMPDL3B negatively regulates innate immunity

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   Lipid metabolism and receptor-mediated signaling are highly intertwined processes that cooperate to fulfill cellular functions and safeguard cellular homeostasis. Activation of Toll-like receptors (TL

3. Towards host-directed therapies for tuberculosis [Comment] (Publications)

   Towards host-directed therapies for tuberculosis [Comment]

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   The treatment of tuberculosis is based on combinations of drugs that directly target Mycobacterium tuberculosis. A new global initiative is now focusing on a complementary approach of developing adjun

4. Using metal ratios to detect emissions from municipal waste incinerators in ambient air pollution data, atmospheric environment (Publications)

   Using metal ratios to detect emissions from municipal waste incinerators in ambient air pollution data, atmospheric environment

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5. Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy (Publications)

   Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy

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   OBJECTIVE: We conducted a community survey to estimate the prevalence and describe the features, risk factors, and consequences of convulsive status epilepticus (CSE) among people with active convulsi

6. The elderly, the young and the pregnant traveler - a retrospective data analysis from a large Swiss Travel Center with a special focus on malaria... (Publications)

   The elderly, the young and the pregnant traveler - a retrospective data analysis from a large Swiss Travel Center with a special focus on malaria prophylaxis and yellow fever vaccination

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   BACKGROUND: Vulnerable individuals such as elderly, children/adolescents and pregnant/breastfeeding women increasingly travel overseas. We describe the travel and vaccination patterns of these groups

7. Pharmacological effects of primaquine ureas and semicarbazides on the CNS in mice and antimalarial activity in vitro (Publications)

   Pharmacological effects of primaquine ureas and semicarbazides on the CNS in mice and antimalarial activity in vitro

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   New primaquine (PQ) urea and semicarbazide derivatives 1-4 were screened for the first time for CNS and antimalarial activity. Behavioural tests were performed on mice. In vitro cytotoxicity on L-6 ce

8. Transport-related measures to mitigate climate change in Basel, Switzerland: a health-effectiveness comparison study (Publications)

   Transport-related measures to mitigate climate change in Basel, Switzerland: a health-effectiveness comparison study

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   BACKGROUND: Local strategies to reduce green-house gases (GHG) imply changes of non-climatic exposure patterns. OBJECTIVE: To assess the health impacts of locally relevant transport-related climate ch

9. Gift from nature: cyclomarin a kills mycobacteria and malaria parasites by distinct modes of action (Publications)

   Gift from nature: cyclomarin a kills mycobacteria and malaria parasites by distinct modes of action

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   Malaria continues to be one of the most devastating human diseases despite many efforts to limit its spread by prevention of infection or by pharmaceutical treatment of patients. We have conducted a s

10. Discovery and optimisation studies of antimalarial phenotypic hits (Publications)

    Discovery and optimisation studies of antimalarial phenotypic hits

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    There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were id