Genetic diversity and protective efficacy of the RTS,S/AS01 malaria vaccine (Publications)
Background The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium falciparum and has partial protective efficacy against clinical and severe malaria disease in infants and children.
Spatial distribution of schistosomiasis and treatment needs in sub-Saharan Africa: a systematic review and geostatistical analysis (Publications)
BACKGROUND: Schistosomiasis affects more than 200 million individuals, mostly in sub-Saharan Africa, but empirical estimates of the disease burden in this region are unavailable. We used geostatistica
International scale implementation of the CNOSSOS-EU road traffic noise predictin model for epidemiological studies (Publications)
The EU-FP7-funded BioSHaRE project is using individual-level data pooled from several national cohort studies in Europe to investigate the relationship of road traffic noise and health. The detailed i
Antiprotozoal effect of <em>Artemisia indica</em> extracts and essential oil (Publications)
Diverse solvent extracts of Artemisia indica leaves originating from the West Bengal region (India) were assessed for the content of artemisinin and characteristic Artemisia polymethoxyflavonoids, nam
Changing from whole-cell to acellular pertussis vaccines would trade superior tolerability for inferior protection (Publications)
Notifications of infant deaths, assumed to be related to the introduction of new pentavalent DTwP-Hib-HBV childhood vaccines, caused, during 2008-2010 in few Asian countries, temporary interruptions o
Costing RTS,S introduction in Burkina Faso, Ghana, Kenya, Senegal, Tanzania, and Uganda: a generalizable approach drawing on publicly available data (Publications)
Recent results from the phase 3 trial of RTS,S/AS01 malaria vaccine show that the vaccine induced partial protection against clinical malaria in infants and children; given the high burden of the dise
No fever, no malaria? A diagnostic challenge in an immunocompromised patient (Publications)
We describe the case of an immunosuppressed women with proven malaria tropicana. Fever was not reported with this patient. We conclude that the concept of using fever as a primary surrogate indicator
Meta-analysis identifies seven susceptibility loci involved in the atopic march (Publications)
Eczema often precedes the development of asthma in a disease course called the 'atopic march'. To unravel the genes underlying this characteristic pattern of allergic disease, we conduct a multi-stage
6-Arylpyrazine-2-carboxamides: a new core for <em>Trypanosoma brucei</em> inhibitors (Publications)
From a whole-organism high throughput screen of approximately 87,000 compounds against Trypanosoma brucei brucei, we recently identified eight new unique compounds for the treatment of human African t
