The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from <em>Xanthium... (Publications)
against T. CRUZI (Chagas disease), LEISHMANIA DONOVANI (Kala-Azar) as well as PLASMODIUM FALCIPARUM (Malaria tropica). Bioactivity-guided fractionation resulted in the isolation of four bioactive sesquiterpene
Systematic review of the entomological impact of insecticide-treated nets evaluated using experimental hut trials in Africa (Publications)
Africa, diminishing the efficacy of insecticide-treated nets (ITNs) – the primary tool for preventing malaria. The entomological efficacy of indoor vector control interventions can be measured in experimental
Characterization of the interaction network of exported proteins in Plasmodium falciparum (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/characterization-of-the-interaction-network-of-exported-proteins-in-plasmodium-falciparum
host cell which are the sole cause of morbidity and mortality. P. falciparum, the deadliest form of malaria, exports during its blood cycle over 10% of its proteome into the host cell leading to major host
Geography and health: role of human translocation and access to care (Publications)
human translocation and access to care" document enhanced disease transmission of diseases, such as malaria, leishmaniasis, schistosomiasis, COVID-19 (Severe acute respiratory syndrome corona 2) and Oropouche
Fine-scale spatial and temporal variations in insecticide resistance in <em>Culex pipiens</em> complex mosquitoes in rural south-eastern Tanzania (Publications)
Culex could negatively influence the acceptability of other interventions such as those used against malaria mosquitoes.
Drones to Deliver Tuberculosis Drugs in Madagascar (News)
https://www.swisstph.ch/en/news/news-detail/news/drones-to-deliver-tuberculosis-drugs-in-madagascar
Tuberculosis (TB) is the leading infectious disease killer globally, surpassing HIV/AIDS and malaria, with 10 million new cases estimated in 2019. Among those, three million cases are undiagnosed or unreported
Smartphone-Based Tool Improves Care of Children in Tanzania (News)
https://www.swisstph.ch/en/news/20172710-e-poct
recommends treatment based both on clinical signs as well as point-of-care test results. Apart from the malaria rapid diagnostic test, the e-POCT includes tests for anemia, low oxygen, bacterial infections, and
Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a "push-pull control strategy" against <em>Aedes... (Publications)
push-pull system. Push-pull systems have been shown to reduce house entry and outdoor biting rates of malaria vectors and so have the potential to control other outdoor biting mosquitoes such as Aedes aegypti
Health and survival of young chlidren in southern Tanzania (Publications)
net use, vaccination, vitamin A, and care-seeking for recent illness, and measured haemoglobin and malaria parasitaemia. RESULTS: In the health facility survey, a prescriber or nurse was present on the day
A major role for the <em>Plasmodium falciparum</em> ApiAP2 protein PfSIP2 in chromosome end biology (Publications)
framework for antigenic variation and evolution of subtelomeric virulence gene families in the malaria parasite Plasmodium falciparum. While recent studies assigned important roles for reversible histone