Efficacy, safety, and dose of pafuramidine, a new oral drug for treatment of first stage sleeping sickness, in a phase 2a clinical study and phase 2b... (Publications)
2b study was open-label, parallel-group, controlled, randomized, and conducted at two sites in the DRC between April 2003 and February 2007. The Phase 2b study was then amended to add an open-label sequence [...] of oral pafuramidine in African patients with first stage HAT. METHODS: The Phase 2a study was an open-label, non-controlled, proof-of-concept study where 32 patients were treated with 100 mg of pafuramidine
Efficacy, safety, and dose of pafuramidine, a new oral drug for treatment of first stage sleeping sickness, in a phase 2a clinical study and phase 2b... (Publications)
2b study was open-label, parallel-group, controlled, randomized, and conducted at two sites in the DRC between April 2003 and February 2007. The Phase 2b study was then amended to add an open-label sequence [...] of oral pafuramidine in African patients with first stage HAT. METHODS: The Phase 2a study was an open-label, non-controlled, proof-of-concept study where 32 patients were treated with 100 mg of pafuramidine
Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese... (Publications)
discovered type of unusual oxygen-bridged naphthylisoquinoline dimers and two previously described "open-chain" analogues, mbandakamines C (10) and D (11). The full absolute stereostructures of these compounds [...] that both spirombandakamine- and cyclombandakamine-type dimers result from the oxidation of their open-chain mbandakamine-type congeners. The new dimeric alkaloids 7-9 displayed potent growth-inhibitory
Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese... (Publications)
discovered type of unusual oxygen-bridged naphthylisoquinoline dimers and two previously described "open-chain" analogues, mbandakamines C (10) and D (11). The full absolute stereostructures of these compounds [...] that both spirombandakamine- and cyclombandakamine-type dimers result from the oxidation of their open-chain mbandakamine-type congeners. The new dimeric alkaloids 7-9 displayed potent growth-inhibitory
PhD in Epidemiology, Public Health and Insurance Medicine | Swiss TPH (Page)
https://www.swisstph.ch/en/study-with-us/doctorate/epidemiology-public-health-and-insurance-medicine
in the Student Handbook. Contact Christine Mensch Course Coordinator PhD at Swiss TPH How to Apply Open PhD Positions at Swiss TPH Swiss TPH Seminars PhD Epidemiology, Faculty of Sciences The Interdisciplinary [...] Interdisciplinary PhD in Epidemiology ('Fakultätsübergreifendes Promotionsfach Epidemiologie') is open to students from a variety of backgrounds, namely biology, medicine, medical biology, microbiology, molecular [...] this option is available on the PhD Program in Health...
MalCommit - Understanding Sexual Commitment and Early Differentiation of Malaria Transmission Stages (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/malcommit-understanding-sexual-commitment-and-early-differentiation-of-malaria-transmission-stages
differentiation of asexual malaria blood stage parasites into sexual forms. The anticipated results may open up new avenues for the development of transmission-blocking drugs and vaccines.
Antimicrobial resistance: the silent pandemic (Page)
https://www.swisstph.ch/en/impact-stories/antimicrobial-resistance-the-silent-pandemic
is on the WHO's list of top 10 global public health threats facing humanity." As borders begin to open up again, what role does travelling play? People hospitalized abroad have quite a high risk of becoming
The Health System Support Program (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/the-health-system-support-program
activities (enrollment, premium collection, identification and claim processing management). Thus, the openIMIS software will be made operational in 9 MHO in order to professionalize insurance activities via: [...] planned for operational processes adaptations and trainings for designated key resources persons of MHO: openIMIS administrators, animators as well as medical officers will be trained. Remote technical support
Impact of vaccination and non-pharmaceutical interventions on SARS-CoV-2 dynamics in Switzerland (Publications)
on model of SARS-CoV-2 dynamics, OpenCOVID, was developed to compare the impact of various vaccination and NPI strategies on the COVID-19 epidemic in Switzerland. OpenCOVID uses the Oxford Containment
The Health System Support Program (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/the-health-system-support-program
activities (enrollment, premium collection, identification and claim processing management). Thus, the openIMIS software will be made operational in 9 MHO in order to professionalize insurance activities via: [...] planned for operational processes adaptations and trainings for designated key resources persons of MHO: openIMIS administrators, animators as well as medical officers will be trained. Remote technical support
