Searched for malaria.

1. Tenfold difference in DNA recovery rate: systematic comparison of whole blood vs. dried blood spot sample collection for malaria molecular... (Publications)

   Tenfold difference in DNA recovery rate: systematic comparison of whole blood vs. dried blood spot sample collection for malaria molecular surveillance

   Relevance:

   BACKGROUND: Molecular and genomic surveillance is becoming increasingly used to track malaria control and elimination efforts. Blood samples can be collected as whole blood and stored at - 20 degrees C

2. Assessing determinants of programmatic performance of community management of malaria, pneumonia, and diarrhea in children in Africa: protocol and... (Publications)

   Assessing determinants of programmatic performance of community management of malaria, pneumonia, and diarrhea in children in Africa: protocol and data collection for a mixed methods evaluation of integrated community case management

   Relevance:

   health program designed to provide integrated community-based care for children with pneumonia, malaria, or diarrhea in hard-to-reach areas of low- and middle-income countries. The foundation of the i

3. Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of... (Publications)

   Haematological consequences of acute uncomplicated <em>falciparum </em>malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

   Relevance:

   falciparum malaria to identify the factors associated with malarial anaemia. METHODS: Individual patient data from eligible antimalarial efficacy studies of uncomplicated P. falciparum malaria, available [...] BACKGROUND: Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. We quantified the haematological response following treatment of [...] = 2.06 [95%CI 1.39-3.05], p < 0.001). CONCLUSIONS: In patients with uncomplicated...

4. Geostatistical modelling and survey sampling designs for malaria control and surveillance (Publications)

   Geostatistical modelling and survey sampling designs for malaria control and surveillance

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5. Improving malaria control by understanding human behaviour (Publications)

   Improving malaria control by understanding human behaviour

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6. Volunteer infection studies accelerate the clinical development of novel drugs against malaria (Publications)

   Volunteer infection studies accelerate the clinical development of novel drugs against malaria

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7. The phylodynamic and spread of the invasive Asian malaria vectors, <em>Anopheles stephensi</em>, in Sudan (Publications)

   The phylodynamic and spread of the invasive Asian malaria vectors, <em>Anopheles stephensi</em>, in Sudan

   Relevance:

   Anopheles stephensi is an invasive Asian malaria vector that initially emerged in Africa in 2012 and was reported in Sudan in 2019. We investigated the distribution and population structure of An. stephensi

8. Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection... (Publications)

   Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density <em>Plasmodium falciparum</em> infections during a controlled human malaria infection study

   Relevance:

   BACKGROUND: Progress towards malaria elimination has stagnated, partly because infections persisting at low parasite densities comprise a large reservoir contributing to ongoing malaria transmission and are difficult [...] and quantitative polymerase chain reaction (qPCR) during a controlled human malaria infection (CHMI) study conducted in malaria exposed adults (NCT03590340). METHODS: Blood samples were collected from healthy [...] administered by direct venous inoculation. qPCR (18s ribosomal...

9. Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite <em>Plasmodium falciparum</em> (Publications)

   Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite <em>Plasmodium falciparum</em>

   Relevance:

   Malaria parasites rely on specialized stages, called gametocytes, to ensure human-to-human transmission. The formation of these sexual precursor cells is initiated by commitment of blood stage parasites [...] vivo. These observations suggest that therapeutic interventions may promote gametocytogenesis and malaria transmission. Here, we engineered a P. falciparum reporter line to quantify sexual commitment rates [...] rates after exposure to antimalarials and other pharmaceuticals commonly...

10. Influence of testing modality on bioefficacy for the evaluation of Interceptor® G2 mosquito nets to combat malaria mosquitoes in Tanzania (Publications)

    Influence of testing modality on bioefficacy for the evaluation of Interceptor® G2 mosquito nets to combat malaria mosquitoes in Tanzania

    Relevance:

    against pyrethroid-resistant strains, demonstrating the usefulness of chlorfenapyr in mitigation of malaria.