An efficient system to generate monoclonal antibodies against membrane-associated proteins by immunisation with antigen-expressing mammalian cells (Publications)
ABSTRACT: BACKGROUND: The generation of monoclonal antibodies specific for protein antigens usually depends on purified recombinant protein for both immunisation and hybridoma screening. Purification
Efficacy and safety of praziquantel in preschool-aged children in an area co-endemic for <em>Schistosoma mansoni</em> and <em>S. haematobium</em> (Publications)
BACKGROUND: In sub-Saharan Africa the recommended strategy to control schistosomiasis is preventive chemotherapy. Emphasis is placed on school-aged children, but in high endemicity areas, preschool-ag
Formation of the circumsporozoite protein of <em>Plasmodium falciparum</em> in <em>Anopheles stephensi</em> (Publications)
The place and time of synthesis of the circumsporozoite protein of P. falciparum was analysed with a monoclonal antibody directed against the (NANP)3 repetitive epitope of the CS protein. By using an
Socio-cultural determinants of adiposity and physical activity in preschool children: a cross-sectional study (Publications)
BACKGROUND: Both individual socio-cultural determinants such as selected parental characteristics (migrant background, low educational level and workload) as well as the regional environment are relat
<em>Plasmodium falciparum</em> heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors (Publications)
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded
Operational performance and analysis of two rabies vaccination campaigns in N'Djamena, Chad (Publications)
Transmission of rabies from animals to people continues despite availability of good vaccines for both human and animal use. The only effective strategy to achieve elimination of dog rabies and the re
Profile: the rusinga health and demographic surveillance system, western Kenya (Publications)
The health and demographic surveillance system on Rusinga Island, Western Kenya, was initiated in 2012 to facilitate a malaria intervention trial: the SolarMal project. The project aims to eliminate m