Real-time and automated monitoring of antischistosomal drug activity profiles for screening of compound libraries (Publications)
Schistosomiasis is a neglected tropical disease that affects over 200 million people annually. As the antischistosomal drug pipeline is currently empty, repurposing of compound libraries has become a
The legacy of ZikaPLAN: a transnational research consortium addressing Zika (Publications)
Global health research partnerships with institutions from high-income countries and low- and middle-income countries are one of the European Commission's flagship programmes. Here, we report on the Z
Depression and cardiovascular disease are not linked by high blood pressure: findings from the SAPALDIA cohort (Publications)
Depression and cardiovascular disease (CVD) are main contributors to the global disease burden and are linked. Pathophysiological pathways through increased blood pressure (BP) are a common focus in s
Symptoms and functional limitations related to respiratory health and carbon monoxide poisoning in Tanzania: a cross sectional study (Publications)
BACKGROUND: The burden of chronic respiratory symptoms and respiratory functional limitations is underestimated in Africa. Few data are available on carbon monoxide (CO) poisoning in sub-Saharan Afric
Antimicrobial resistance through the lens of One Health in Ethiopia: a review of the literature among humans, animals, and the environment (Publications)
OBJECTIVES: We aimed to review and describe antimicrobial resistance (AMR) prevalence in humans, animals, and the environment in Ethiopia. METHODS: We conducted a structured review of the literature o
Non-Markovian modelling highlights the importance of age structure on Covid-19 epidemiological dynamics (Publications)
The Covid-19 pandemic outbreak was followed by a huge amount of modelling studies in order to rapidly gain insights to implement the best public health policies. Most of these compartmental models inv
Isolation and structural elucidation of compounds from <em>Pleiocarpa bicarpellata</em> and their <em>in vitro</em> antiprotozoal activity (Publications)
Species of the genus Pleiocarpa are used in traditional medicine against fever and malaria. The present study focuses on the isolation and identification of bioactive compounds from P. bicarpellata ex
Drinking water chlorination has minor effects on the intestinal flora and resistomes of Bangladeshi children (Publications)
Healthy development of the gut microbiome provides long-term health benefits. Children raised in countries with high infectious disease burdens are frequently exposed to diarrhoeal pathogens and antib
Discovery, biosynthetic origin, and heterologous production of massinidine, an antiplasmodial alkaloid (Publications)
Bacteria of the genus Massilia represent an underexplored source of bioactive natural products. Here, we report the discovery of massinidine (1), a guanidine alkaloid with antiplasmodial activity, fro
Influence of testing modality on bioefficacy for the evaluation of Interceptor® G2 mosquito nets to combat malaria mosquitoes in Tanzania (Publications)
BACKGROUND: Insecticide-treated net (ITN) durability is evaluated using longitudinal bioefficacy and fabric integrity sampling post-distribution. Interceptor((R)) G2 was developed for resistance manag
