Community knowledge, attitude, practices and beliefs associated with persistence of malaria transmission in north-western and southern regions of... (Publications)
cause of malaria, and thought that it is caused by bathing and drinking un-boiled water, or consuming contaminated food that has malaria parasites without warming it. Reported barriers to malaria prevention [...] Kigoma, Mtwara and Ruvuma) with persistently high malaria transmission for more than two decades. RESULTS: Most of the participants had good knowledge of malaria and how it is transmitted but some FGD participants [...] economic activities that potentially contributed to persistence of ...
Malaria rapid diagnostic tests reliably detect asymptomatic <em>Plasmodium falciparum</em> infections in school-aged children that are infectious to... (Publications)
this study, malaria rapid diagnostic tests (mRDT), light microscopy (LM) and quantitative polymerase chain reaction (qPCR) were used to evaluate their performance detecting asymptomatic malaria infections [...] BACKGROUND: Asymptomatic malaria infections (Plasmodium falciparum) are common in school-aged children and represent a disease transmission reservoir as they are potentially infectious to mosquitoes. To [...] was 31.7% by qPCR, 18.2% by mRDT and 9.4% by LM. Approximately one-third (31.2%)...
Comparison of fine-scale malaria strata derived from population survey data collected using RDTs, microscopy and qPCR in south-eastern Tanzania (Publications)
BACKGROUND: Malaria-endemic countries are increasingly adopting data-driven risk stratification, often at district or higher regional levels, to guide their intervention strategies. The data typically
Therapeutic development to accelerate malaria control through intentional intervention layering (Publications)
significant advancements in the prevention of Plasmodium falciparum malaria. These innovations could support regions in accelerating malaria control, transforming existing intervention packages by supplementing [...] studies of new medical products, sufficiently capture the broader goal of accelerating malaria control? Layering novel malaria products requires monitoring health outcomes that reflect the novel product's targeted [...] offering an entirely new tool. However, to layer new medical...
A combined school survey and reactive case detection reveals minimal local transmission of malaria in the Highlands Region of Papua New Guinea (Publications)
Highlands of Papua New Guinea are non-endemic for malaria compared to the rest of the country. This study aimed to explore the local transmission of malaria in the Highlands through a cross-sectional school [...] 1048 household members were screened for malaria using Rapid Diagnostic Tests, subsequently validated by light microscopy. In addition, an analysis of malaria cases (2017 to 2019) was conducted across [...] Local malaria transmission appears to be minimal in the surveyed Highlands...
A matter of timing: biting by malaria-infected <em>Anopheles</em> mosquitoes and the use of interventions during the night in rural south-eastern... (Publications)
Knowing when and where infected mosquitoes bite is required for estimating accurate measures of malaria risk, assessing outdoor exposure, and designing intervention strategies. This study combines secondary [...] behaviour survey and an entomological survey carried out in the same area to estimate human exposure to malaria-infected Anopheles mosquitoes throughout the night in rural villages in south-eastern Tanzania. [...] Individuals were mainly outdoors before 9PM, and mainly indoors between...
Insights into the biology and insecticide susceptibility of the secondary malaria vector <em>Anopheles parensis</em> in an area with long-term use of... (Publications)
at least 11 sibling species, with Anopheles funestus Giles being the most studied and significant malaria vector. Other species, like Anopheles parensis, are understudied despite their potential role in [...] lity of An. parensis. Primarily feeding on non-human hosts, An. parensis is less significant in malaria transmission than more anthropophilic vectors. Unlike the pyrethroid-resistant An. funestus sensu [...] findings provide a foundation for future research and may inform control strategies...