Mapping hotspots of malaria transmission from pre-existing hydrology, geology and geomorphology data in the pre-elimination context of Zanzibar,... (Publications)
BackgroundLarval source management strategies can play an important role in malaria elimination programmes, especially for tackling outdoor biting species and for eliminating parasite and vector populations [...] larval source management requires tools for identifying geographic foci of vector proliferation and malaria transmission where these efforts may be concentrated. Previous studies have relied on surface topographic [...] examine the relationship between dry and wet season spatial...
Estimating malaria burden in Nigeria: a geostatistical modelling approach (Publications)
This study has produced a map of malaria prevalence in Nigeria based on available data from the Mapping Malaria Risk in Africa (MARA) database, including all malaria prevalence surveys in Nigeria that [...] correlating with malaria presence were land surface temperature for day and rainfall. It was also found that malaria prevalence increased with distance to water bodies up to 4 km. The malaria risk map estimated [...] low malaria prevalence were found to be scattered around the country with...
Spatially aggregated clusters and scattered smaller loci of elevated malaria vector density and human infection prevalence in urban Dar es Salaam,... (Publications)
density and eight of malaria infection prevalence were detected over both phases. Only a third of vectors were collected in hotspots in phase 1 (30 %) and phase 2 (33 %). Malaria prevalence hotspots accounted [...] BACKGROUND: Malaria transmission, primarily mediated by Anopheles gambiae, persists in Dar es Salaam (DSM) despite high coverage with bed nets, mosquito-proofed housing and larviciding. New or improved [...] improved vector control strategies are required to eliminate malaria from...
A malaria risk map of Kinshasa, Democratic Republic of Congo (Publications)
This study presents the first malaria risk map of Kinshasa, a mega city of roughly 10 million inhabitants and located in a highly endemic malaria zone. Prevalence of malaria, anaemia and reported fever was [...] prevalence for malaria and anaemia was 6.4 % (5.6-7.4) and 65.1 % (63.7-66.6) in 2009, and 17.0 % (15.7-18.3) and 64.2 % (62.6-65.9) in 2011. In two HZs sampled in both surveys, malaria prevalence was [...] BACKGROUND: In Kinshasa, malaria remains a major public health problem but its...
Comparative performance of three experimental hut designs for measuring malaria vector responses to insecticides in Tanzania (Publications)
BACKGROUND: Experimental huts are simplified, standardized representations of human habitations that provide model systems to evaluate insecticides used in indoor residual spray (IRS) and long-lasting
Estimating malaria transmission intensity from <em>Plasmodium falciparum</em> serological data using antibody density models (Publications)
BACKGROUND: Serological data are increasingly being used to monitor malaria transmission intensity and have been demonstrated to be particularly useful in areas of low transmission where traditional measures
Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved <em>Plasmodium falciparum</em>... (Publications)
Controlled human malaria infection (CHMI) by mosquito bite has been used to assess new anti-malaria interventions in > 1,500 volunteers since development of methods for infecting mosquitoes by feeding