How Gold Mining Affects the Spread of Malaria (News)
https://www.swisstph.ch/en/news/news-detail/news/how-gold-mining-affects-the-spread-of-malaria
using black market medicines further increase the risk of malaria transmission. “The international gold price has been the best predictor of malaria rates in Guyana,” said Pablo De Salazar from Swiss TPH [...] higher risk of malaria transmission. A recently published case study by Swiss TPH and partners analysed how Brazil’s 2023 crackdown on illegal gold mining in Yanomami lands triggered a malaria outbreak in [...] the rise in malaria cases in Guyana, demonstrating how the displacement of...
New Study Links Climate Change to Malaria Increase in Northern Kenya (News)
https://www.swisstph.ch/en/news/news-detail/news/new-study-links-climate-change-to-malaria-increase-in-northern-kenya
changes such as urbanization and malaria control interventions, are affecting the spread of malaria in Kenya. “By employing advanced geostatistical models based on national malaria surveys conducted between 2015 [...] to combat malaria amidst changing environmental conditions.” Malaria trends and climatic factors The study found that between 2015 and 2020, Kenya saw a promising decline in overall malaria prevalence [...] Monitoring and Training for Malaria Control and Elimination and a member of...
Papua New Guinea National Malaria Control Programme Evaluation and Operational Research 2021 to 2023 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/papua-new-guinea-national-malaria-control-programme-evaluation-and-operational-research-2021-to-2023
exhibits a complex malaria epidemiology with marked heterogeneity in malaria transmission. With financial support from the Global Fund to Fight AIDS, Tuberculosis and Malaria, the National Malaria Control Program [...] across PNG to assess quality of malaria case management. Activity 2: a national Malaria Indicator Survey (MIS) to track progress in malaria intervention coverage and malaria prevalence on national and regional [...] changing malaria epidemiology in PNG (including aspects related...
Mathematical models to define new malaria immunotherapies and interventions to meet public health needs (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/mathematical-models-to-define-new-malaria-immunotherapies-and-interventions-to-meet-public-health-needs
progress in fighting malaria, there remains a need for new antimalarial interventions to protect children and other vulnerable populations who experience the highest burden of malaria. Developing new in [...] from academia, product development partners, and representatives from malaria-endemic countries. Our focus is on next-generation malaria vaccines, monoclonal antibodies, and new chemoprevention antimalarials
Evaluation of the Papua New Guinea National Malaria Control Program, 2018-2020 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/evaluation-of-the-papua-new-guinea-national-malaria-control-program-2018-2020
information on malaria control intervention coverage, prevalence of malaria infection, and on different aspects of the changing malaria epidemiology in PNG, including on the local transmission of malaria in the [...] distinct malaria burden amenable to different combinations of interventions) Activity 2: School Malaria Survey (assessing malaria prevalence in school aged schildren) Activity 3: National Malaria Indicator [...] considered the country with the highest malaria transmission outside of...
Iron fortified complementary foods containing a mixture of sodium iron EDTA with either ferrous fumarate or ferric pyrophosphate reduce iron... (Publications)
health problem in sub-Saharan Africa. The efficacy of iron fortification against IDA is uncertain in malaria-endemic settings. The objective of this study was to evaluate the efficacy of a complementary food [...] fumarate (FeFum) or ferric pyrophosphate (FePP) to combat IDA in preschool-age children in a highly malaria endemic region. This is a secondary analysis of a nine-month cluster-randomized controlled trial [...] treatment interaction on Hb or total anemia. These data indicate that,...
Transcriptional profiling defines histone acetylation as a regulator of gene expression during human-to-mosquito transmission of the malaria parasite... (Publications)
Transmission of the malaria parasite Plasmodium falciparum from the human to the mosquito is mediated by the intraerythrocytic gametocytes, which, once taken up during a blood meal, become activated to [...] essential role of histone acetylation for gene regulation in gametocytes, which can be exploited for malaria transmission-blocking interventions.
