Identifying key factors of the transmission dynamics of drug-resistant malaria (Publications)
Development of resistance to malaria treatments remains a great threat to continued malaria burden reduction and elimination. Quantifying the impact of key factors which increase the emergence and spread
Inter-sectoral approaches for the prevention and control of malaria among the mobile and migrant populations: a scoping review (Publications)
knowledge about malaria, initiation and promotion of bed nets utilization, increased access to diagnosis and treatment in a surveillance context and contributed towards a reduction in malaria transmission [...] with correct knowledge about malaria transmission (70%, 95% CI 57-83%). Interventions targeting the use of bed nets utilization were two times more likely to reduce malaria incidence amongst the targeted [...] BACKGROUND: Malaria cases among mobile and migrant populations (MMPs) represent...
The promise, problems and pitfalls of mass drug administration for malaria elimination: a qualitative study with scientists and policymakers (Publications)
mass drug administration (MDA). This article explores attitudes towards and perceptions of MDA for malaria elimination among policymakers and leading malariologists. Methods: Thirty-two semistructured interviews [...] with policymakers (n=17) and principal investigators (n=15) selected based on their involvement in malaria prevention, control and elimination in the GMS. Interviews were audio recorded and transcribed for [...] Results: Researchers and policymakers described reluctance and...
Diagnostic performance of conventional and ultrasensitive rapid diagnostic tests for malaria in febrile outpatients in Tanzania (Publications)
Background: A novel ultra-sensitive malaria RDT (us-RDT) has been developed for improved active P.falciparum case detection. The utility of this us-RDT in clinical diagnosis and fever management has not [...] infections. Conclusion: There is neither gain nor risk to apply us-RDT rather than co-RDT for clinical malaria diagnosis. In febrile patients, only a small proportion of infections are characterized by parasite
Spatial-temporal heterogeneity in malaria receptivity is best estimated by vector biting rates in areas nearing elimination (Publications)
when vector control can be withdrawn after malaria is eliminated depend on the receptivity or potential of an area to support vector populations. To guide malaria control and elimination programmes, the potential [...] estimate malaria receptivity and transmission were compared within and among geographically localised villages of active transmission in the Western Province of the Solomon Islands. RESULTS: Malaria transmission [...] inoculation and parity rates could not be measured with the...
Nationwide school malaria parasitaemia survey in public primary schools, the United Republic of Tanzania (Publications)
school, malaria survey was implemented to assess the risk factors of malaria prevalence and bed net use among primary school children in mainland Tanzania. This allowed the mapping of malaria prevalence [...] for malaria infection and for bed net use while adjusting for school effect. RESULTS: In total, 49,113 children were interviewed and tested for malaria infection. The overall prevalence of malaria was [...] prevalence at council level and assessment of malaria risk factors among school...
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background (Publications)
The predisposition of parasites acquiring artemisinin resistance still remains unclear beyond the mutations in Pfk13 gene and modulation of the unfolded protein response pathway. To explore the chain
