Modelling reactive case detection strategies for interrupting transmission of <em>Plasmodium falciparum</em> malaria (Publications)
BACKGROUND: As areas move closer to malaria elimination, a combination of limited resources and increasing heterogeneity in case distribution and transmission favour a shift to targeted reactive inter
<em>N</em>-substituted noscapine derivatives as new antiprotozoal agents: synthesis, antiparasitic activity and molecular docking study (Publications)
Novel N-substituted noscapine derivatives were synthesized by a three-component Strecker reaction of cyclic ether of N-nornoscapine with varied aldehydes, in the presence of cyanide ion. Moreover, the
Therapeutic efficacy of albendazole against soil-transmitted helminthiasis in children measured by five diagnostic methods (Publications)
BACKGROUND: Preventive chemotherapy (PC) with benzimidazole drugs is the backbone of soil-transmitted helminth (STH) control programs. Over the past decade, drug coverage has increased and with it, th
Insight into potassium's role in childhood mortality due to severe acute malnutrition (Publications)
Hypokalaemia is associated with an increase in mortality in children with severe acute malnutrition (SAM) and diarrhoea. This is a descriptive cross-sectional retrospective study conducted in the Nutr
Models of effectiveness of interventions against malaria transmitted by <em>Anopheles albimanus</em> (Publications)
BACKGROUND: Most impact prediction of malaria vector control interventions has been based on African vectors. Anopheles albimanus, the main vector in Central America and the Caribbean, has higher intr
Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted... (Publications)
BACKGROUND: Because the success of deworming programs targeting soil-transmitted helminths (STHs) is evaluated through the periodically assessment of prevalence and infection intensities, the use of t
Malaria-anemia comorbidity prevalence as a measure of malaria-related deaths in sub-Saharan Africa (Publications)
Different methods and data sources have been utilized to determine the relationship between malaria and mortality in endemic countries. Most of these efforts have focused on deaths directly attributed
Kankanet: an artificial neural network-based object detection smartphone application and mobile microscope as a point-of-care diagnostic aid for... (Publications)
BACKGROUND: Endemic areas for soil-transmitted helminthiases often lack the tools and trained personnel necessary for point-of-care diagnosis. This study pilots the use of smartphone microscopy and an