Subspecies typing of <em>Streptococcus agalactiae</em> based on ribosomal subunit protein mass variation by MADLI-TOF MS (Publications)
Background: A ribosomal subunit protein (rsp)-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) method was developed for fast subspecies-level typing of
Influence of acute physical activity on stress reactivity in obese and normal weight children: a randomized controlled trial (Publications)
OBJECTIVE: Physical activity (PA) may influence acute stress reactivity in children differently depending on their weight. This randomized controlled trial investigated the impact of acute PA and of B
Machine learning techniques for personalized breast cancer risk prediction: comparison with the BCRAT and BOADICEA models (Publications)
BACKGROUND: Comprehensive breast cancer risk prediction models enable identifying and targeting women at high-risk, while reducing interventions in those at low-risk. Breast cancer risk prediction mod
Performance and impact of GeneXpert MTB/RIF® and Loopamp MTBC Detection Kit® assays on tuberculosis case detection in Madagascar (Publications)
BACKGROUND: Tuberculosis rapid molecular assays, including GeneXpert MTB/RIF(R) and Loopamp MTBC Detection Kit(R), are highly sensitive and specific. Such performance does not automatically translate
Excellence in Research, Services, Education and Management - Recognized by EFQM application 2022 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/excellence-in-research-services-education-and-management-recognized-by-efqm-application-2022
The Swiss TPH roadmap towards excellence according to the EFQM (European Foundation for Quality Management) provides for a two-stage approach: a) EFQM C2E "Committed to Excellence" could be implemente
Moxidectin for Strongyloidiasis (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/moxidectin-for-strongyloidiasis
The overarching goal of this project is to assemble for the first time key data on the safety and efficacy and pharmacokinetics of moxidectin for the treatment of strongyloidiasis. We propose to condu
Switch Either near Suppression Or THOusand – switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/switch-either-near-suppression-or-thousand-switch-to-second-line-versus-who-guided-standard-of-care-for-unsuppressed-patients-on-first-line-art-with-viremia-below-1000-copies/ml-a-multicenter-open-label-randomized-clinical-trial
Background The World Health Organization (WHO) recommends viral load (VL) measurement as the preferred monitoring strategy for HIV-infected individuals on antiretroviral therapy (ART) in resource-limi