PCR correction strategies for malaria drug trials: updates and clarifications (Publications)
Malaria drug trials conducted in endemic areas face a major challenge in their analysis because it is difficult to establish whether parasitaemia in blood samples collected after treatment indicate drug [...] public and private bodies who are working on the development, deployment, and surveillance of new malaria drugs. We aim to promote discussion around these issues and argue for the adoption of improved s
Multiplicity of asymptomatic <em>Plasmodium falciparum </em>infections and risk of clinical malaria: a systematic review and pooled analysis of... (Publications)
subsequent febrile malaria or with an increased risk. CONCLUSIONS: The number of clones in asymptomatic P. falciparum infections is associated with different risks of subsequent clinical malaria depending on [...] BACKGROUND: The malaria parasite Plasmodium falciparum holds an extensive genetic polymorphism. In this pooled analysis, we investigate how the multiplicity, i.e. the number of co-infecting clones, in [...] in asymptomatic P. falciparum infections affects the subsequent risk of...
Eave ribbons treated with transfluthrin can protect both users and non-users against malaria vectors (Publications)
treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, and could constitute a scalable and low-cost supplement to current interventions, such [...] ribbons alone. CONCLUSION: Transfluthrin-treated eave ribbons protect both users and non-users against malaria mosquitoes indoors and outdoors. The mosquito-killing property of transfluthrin can magnify the communal
Provision of a Scoping Study for a Strategic Environmental Assessment (SEA) on behalf of Target Malaria (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/provision-of-a-scoping-study-for-a-strategic-environmental-assessment-sea-on-behalf-of-target-malaria
Genetically modified mosquitoes represent great potential for malaria control. Any future application of gene drive mosquitoes for malaria control will require many elements, including policy action, [...] to suppress populations of malaria vector mosquitoes. The assessments main objectives are to: (i) raise awareness amongst policy makers of genetic control tools for malaria using gene drives (ii) develop [...] gene drive (the action) and subsequent reduction of malaria (the desired effect)...
Spatio-temporal modelling to assess the impact of climate change on the burden of malaria and to support early warning systems (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/spatio-temporal-modelling-to-assess-the-impact-of-climate-change-on-the-burden-of-malaria-and-to-support-early-warning-systems
climate variability, land use, malaria vector control coverage and socio-economic factors to changes in malaria incidence and mortality; (ii) develop stochastic metapopulation malaria transmission models which [...] statistical models to forecast malaria; (iv) evaluate the effects of environmental vector-control with microbial larvicides on the burden of malaria; and (v) project future malaria burden based on scenarios [...] changes, malaria interventions and socioeconomic effects, which are...
BACKUP Health Cameroon - Improving Access to Malaria Care and Services for Children Under Five: Pilot Project (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/backup-health-cameroon-improving-access-to-malaria-care-and-services-for-children-under-five-pilot-project
approximately $101 million will go to malaria treatment and control programs. These funds are expected to be absorbed through the end of 2023. The National Malaria Control Program (PNLP) is working towards [...] groups of activities: Estimation of the costs of malaria treatment services and care: The aim is to propose three cost models for the management of all malaria care: "basic", "standard" and "comprehensive" [...] goal is to customize openIMIS to meet the needs of malaria care management....
Malawi Malaria Indicator Survey Quality Assurance Services (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/malawi-malaria-indicator-survey-quality-assurance-services
Malaria indicator surveys are an important source of data on disease burden (parasite prevalence, fever prevalence, etc), and coverage of malaria prevention and case management interventions, particularly [...] decisions. The objective of this mandate of Global Fund was to assess the extent to which the Malawi malaria indicator survey 2021 activities were planned, coordinated, and executed according to the standard
Global Malaria Technical & Training Support Package, Phase 3 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/global-malaria-technical-training-support-package-phase-3
global malaria control and elimination by shaping global and national malaria control and elimination policies, and ultimately to reduce the malaria burden and to increase the number of malaria-free zones [...] and national malaria strategies. Background Thanks to the scale-up of effective malaria vector control tools such as insecticide-treated mosquito nets, diagnostics and medicines, malaria mortality has [...] Back Malaria action plan, aligned with the 2016-2030 timeline of the Sustainable...