Thermotherapy of Buruli Ulcer at Community Level, Cameroon (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/thermotherapy-of-buruli-ulcer-at-community-level-cameroon
Treatment of the neglected tropical skin disease Buruli Ulcer (BU) relies currently on a single drug, rifampicin, which is given in combination with streptomycin. Development of an alternative treatme
Lufthygienische Dokumentationsstelle 2018-2021 (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/lufthygienische-dokumentationsstelle-2018-2021
Die vom Bundesamt für Umwelt (BAFU) finanzierte Dokumentationsstelle LUDOK am Schweizerischen Tropen und Public Health Institut (Swiss TPH) liefert seit 30 Jahren evidenzbasierte Informationen zu den
Efficacy and safety of fexinidazole in patients with Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense: a multicentre,... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/efficacy-and-safety-of-fexinidazole-in-patients-with-human-african-trypanosomiasis-hat-due-to-trypanosoma-brucei-rhodesiense-a-multicentre-open-label-clinical-trial
A vector-borne parasitic illness, human African trypanosomiasis (HAT), also known as sleeping sickness, is usually fatal without treatment. The less prevalent form, T.b. rhodesiense (r-HAT), is concen
Evolution and Epidemiology of Rifampicin-Resistant Tuberculosis in Khayelitsha, Cape Town: Implications for Biology and Disease Control (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/evolution-and-epidemiology-of-rifampicin-resistant-tuberculosis-in-khayelitsha-cape-town-implications-for-biology-and-disease-control
Background Bacteria resistant to multiple antibiotics are a growing threat for global public health and the economy. Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant TB (XDR-TB
Drug discovery and development for schistosomiasis: From repositioning of antimalarial drug leads and clinical advanced drug candidates to the... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/drug-discovery-and-development-for-schistosomiasis-from-repositioning-of-antimalarial-drug-leads-and-clinical-advanced-drug-candidates-to-the-development-of-a-new-paediatric-formulation-of-praziquantel
The aim of my 4-year research project is to identify one or several antischistosomal drug development candidates targeting the haemoglobin degradation pathway and/or other mechanisms with favourable p
Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)
OBJECTIVE: Inflammatory risk factors in childhood, e.g. obesity, impact on carotid artery intima media thickness (CIMT), an early indicator of atherosclerosis. Little is known on potential infectious
Genes interacting with occupational exposures to low molecular weight agents and irritants on adult-onset asthma in three European studies (Publications)
BACKGROUND: The biological mechanisms by which cleaning products and disinfectants - an emerging risk factor - affect respiratory health remain incompletely evaluated. Studying genes by environment in
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)
HapMap imputed genome-wide association studies (GWAS) have revealed > 50 loci at which common variants with minor allele frequency > 5% are associated with kidney function. GWAS using more complete re
