Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age (Publications)
BACKGROUND: Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal develop
Ensemble modeling highlights importance of understanding parasite-host behavior in preclinical antimalarial drug development (Publications)
Emerging drug resistance and high-attrition rates in early and late stage drug development necessitate accelerated development of antimalarial compounds. However, systematic and meaningful translation
Molecular detection of <em>Rickettsia </em>spp., <em>Borrelia </em>spp., <em>Bartonella </em>spp. and <em>Yersinia pestis</em> in ectoparasites of... (Publications)
Little is known about the presence of vector-borne bacteria in southwest Madagascar. Anthropogenic alteration of natural habitats represents an important driver for the emergence of new diseases. Espe
Secreted microRNA data from the parasitic filarial nematode <em>Acanthocheilonema viteae</em> (Publications)
microRNAs (miRNAs) are an abundant class of non-coding RNA species with important regulatory roles in gene expression at the posttranscriptional level. The helminth Acanthocheilonema viteae serves as
Parental satisfaction with quality of neonatal care in different level hospitals: evidence from Vietnam (Publications)
BACKGROUND: Most health systems provide the most specialized, and presumably also the highest quality of care at a central level. This study assessed parental satisfaction and its determinants in the
Advancing global health through environmental and public health tracking (Publications)
Global environmental change has degraded ecosystems. Challenges such as climate change, resource depletion (with its huge implications for human health and wellbeing), and persistent social inequaliti
Phototemtide A, a cyclic lipopeptide heterologously expressed from<em> Photorhabdus temperata </em>Meg1, shows selective antiprotozoal activity (Publications)
A new cyclic lipopeptide, phototemtide A (1), was isolated from Escherichia coli expressing the biosynthetic gene cluster pttABC from Photorhabdus temperata Meg1. The structure of 1 was elucidated by
Preclinical antimalarial combination study of M5717, a <em>Plasmodium falciparum</em> elongation factor 2 inhibitor, and pyronaridine, a hemozoin... (Publications)
Antimalarial drug resistance in the Plasmodium falciparum parasite poses a constant challenge for drug development. To mitigate this risk, new antimalarial medicines should be developed as fixed-dose
Short term association between ozone and mortality: global two stage time series study in 406 locations in 20 countries (Publications)
OBJECTIVE: To assess short term mortality risks and excess mortality associated with exposure to ozone in several cities worldwide. DESIGN: Two stage time series analysis. SETTING: 406 cities in 20 co
