Delay in diagnosis of pulmonary tuberculosis increases the risk of pulmonary cavitation in pastoralist setting of Ethiopia (Publications)
BACKGROUND: Delay in diagnosis and treatment of pulmonary tuberculosis (PTB) leads to severe disease, adverse outcomes and increased transmission. Assessing the extent of delay and its effect on disea
Development of a recombinase polymerase amplification (RPA) fluorescence assay for the detection of <em>Schistosoma haematobium</em> (Publications)
BACKGROUND: Accurate diagnosis of urogenital schistosomiasis is vital for surveillance and control programmes. While a number of diagnostic techniques are available there is a need for simple, rapid a
Are out-of-school adolescents at higher risk of adverse health outcomes? Evidence from 9 diverse settings in sub-Saharan Africa (Publications)
OBJECTIVES: We analyzed mutually comparable surveys on adolescent attitudes and behaviors from nine sites in seven sub-Saharan African countries, to determine the relationship between school enrollmen
Estimation of malaria-attributable fever in malaria test-positive febrile outpatients in three provinces of Mozambique, 2018 (Publications)
Like most malaria-endemic countries, Mozambique relies on tabulation of confirmed malaria test-positive febrile patients to track incidence of malaria. However, this approach is potentially biased by
Nutritional status of Tajik children and women: transition towards a double burden of malnutrition (Publications)
The double burden of malnutrition, an emerging concern in developing countries, can exist at various levels: individual, household, and population. Here, we explore the nutritional status of Tajik wom
The <em>Plasmodium falciparum</em> Hsp70-x chaperone assists the heat stress response of the malaria parasite (Publications)
Plasmodium falciparum is the most lethal of human-infective malaria parasites. A hallmark of P. falciparum malaria is extensive remodeling of host erythrocytes by the parasite, which facilitates the d
A new chemotype with promise against <em>Trypanosoma cruzi</em> (Publications)
Pyridyl benzamide 2 is a potent inhibitor of Trypanosoma cruzi, but not other protozoan parasites, and had a selectivity-index of > /=10. The initial structure-activity relationship (SAR) indicates th