Identifying risk factors for <em>Plasmodium </em>infection and anaemia in Kinshasa, Democratic Republic of Congo (Publications)
risk factors for malaria infection in large cities in central Africa and in all age groups. There may be different associations with the risk factors for areas with different malaria transmission intensities [...] (non-rural), collected during a cross sectional malaria survey in 2011. Logistic regression with random effects was used to investigate predictors for malaria and anaemia. Differences in risk factors in areas [...] whereas it increased with malaria infection and reported fever. ITN use...
CALINA Study Shows Positive Efficacy and Safety Data for a Novel Treatment for Small Babies (News)
https://www.swisstph.ch/en/news/news-detail/news/calina-study-shows-positive-efficacy-and-safety-data-for-a-novel-treatment-for-babies
Malaria exerts a massive burden on public health across the world, particularly in Africa. Huge strides have been made in recent decades in the treatment of malaria. However, to date, little data has been [...] – babies less than 5 kg. Closing the malaria treatment gap The CALINA study is led by Novartis, with the scientific and financial support of Medicines for Malaria Venture (MMV), and as part of the PAMAfrica [...] in babies under 5kg. Infants under 5 kg can be affected by placental malari...
MATIAS (Page)
https://www.swisstph.ch/en/about/med/medicines-implementation-research/matias
for treatment of severe malaria caused by Plasmodium falciparum . These results with high quality evidence led to a change in the WHO guidelines for the treatment of severe malaria in children and adults [...] Key Project | MATIAS Treatment of Severe Malaria with Injectable Artesunate Implementation Non-Controlled Longitudinal Observational Study to Support Artesunate Introduction in the Democratic Republic [...] the Congo (DRC) In 2010, the AQUAMAT study demonstrated that, in children, the...
Absence of dry season <em>Plasmodium</em> parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in presschool-aged... (Publications)
epidemiology of malaria in the Senegal River Gorgol valley, southern Mauritania, requires particular attention in the face of ongoing and predicted environmental and climate changes. While "malaria cases" are [...] ons in neighbouring regions point to an absence of malaria transmission in mosquito vectors in the dry season. Because the clinical signs of malaria are non-specific and overlap with those of other diseases [...] diseases (e.g. acute respiratory infections and diarrhoea), new research...
Absence of dry season <em>Plasmodium</em> parasitaemia, but high rates of reported acute respiratory infection and diarrhoea in presschool-aged... (Publications)
epidemiology of malaria in the Senegal River Gorgol valley, southern Mauritania, requires particular attention in the face of ongoing and predicted environmental and climate changes. While "malaria cases" are [...] ons in neighbouring regions point to an absence of malaria transmission in mosquito vectors in the dry season. Because the clinical signs of malaria are non-specific and overlap with those of other diseases [...] diseases (e.g. acute respiratory infections and diarrhoea), new research...
Further development of simulations of Plasmodium falciparum interventions and their integration with the needs of stakeholders II (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/further-development-of-simulations-of-plasmodium-falciparum-interventions-and-their-integration-with-the-needs-of-stakeholders-ii
models for predicting the effects of different malaria interventions. It is centered on contributions to the multi-group Bill and Melinda Gates Foundation Malaria Modeling Consortium (MMC). Specific areas [...] e of malaria, of residual transmission, of prioritization and targeting of interventions, and modeling of surveillance-response systems. One important tool used in the project is the OpenMalaria open source [...] including analyses of health systems, pharmacodynamics, and entomological...
Global diversity and balancing selection of 23 leading <em>Plasmodium falciparum </em>candidate vaccine antigens (Publications)
leading vaccine candidate antigens of P. falciparum using the MalariaGEN Pf3K (version 5.1) resource, comprising more than 2600 genomes from 15 malaria endemic countries. A stringent variant calling pipeline [...] genes encoding 23 leading and novel candidate malaria vaccine antigens including csp, trap, eba175, ama1, rh5, and CelTOS. Our analysis shows that current malaria vaccine formulations are based on rare haplotypes [...] Investigation of the diversity of malaria parasite antigens can...
Global diversity and balancing selection of 23 leading <em>Plasmodium falciparum </em>candidate vaccine antigens (Publications)
leading vaccine candidate antigens of P. falciparum using the MalariaGEN Pf3K (version 5.1) resource, comprising more than 2600 genomes from 15 malaria endemic countries. A stringent variant calling pipeline [...] genes encoding 23 leading and novel candidate malaria vaccine antigens including csp, trap, eba175, ama1, rh5, and CelTOS. Our analysis shows that current malaria vaccine formulations are based on rare haplotypes [...] Investigation of the diversity of malaria parasite antigens can...
Analysis and mapping of prospective sources of funding for additional contributions to MEMTI (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/analysis-and-mapping-of-prospective-sources-of-funding-for-additional-contributions-to-memti
The Global Fund to Fight AIDS, Tuberculosis and Malaria set aside funding to incentivize the acceleration of efforts towards elimination of malaria in four countries in the Asia-Pacific region: Papua New [...] New Guinea, Solomon Islands, Vanuatu and Timor-Leste. This "Malaria Elimination in Melanesia and Timor-Leste Initiative" (MEMTI) is additional to Global Fund country funding allocations and is intended [...] development partners. Regarding the identification of all sources of funding for...
Analysis and mapping of prospective sources of funding for additional contributions to MEMTI (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/analysis-and-mapping-of-prospective-sources-of-funding-for-additional-contributions-to-memti
The Global Fund to Fight AIDS, Tuberculosis and Malaria set aside funding to incentivize the acceleration of efforts towards elimination of malaria in four countries in the Asia-Pacific region: Papua New [...] New Guinea, Solomon Islands, Vanuatu and Timor-Leste. This "Malaria Elimination in Melanesia and Timor-Leste Initiative" (MEMTI) is additional to Global Fund country funding allocations and is intended [...] development partners. Regarding the identification of all sources of funding for...
