<em>SERPINA1 </em>methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based... (Publications)
BACKGROUND: The pathophysiological role of SERPINA1 in respiratory health may be more strongly determined by the regulation of its expression than by common genetic variants. A family based study of p
Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission (Publications)
BACKGROUND: Current strategies to control mosquito-transmitted infections use insecticides targeted at various stages of the mosquito life-cycle. Control is increasingly compromised by the evolution o
Predictors of residual antimalarial drugs in the blood in community surveys in Tanzania (Publications)
BACKGROUND: Understanding pattern of antimalarials use at large scale helps ensuring appropriate use of treatments and preventing the spread of resistant parasites. We estimated the proportion of indi
Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community... (Publications)
BACKGROUND: Submicroscopic malaria infections contribute to transmission in exposed populations but their extent is underestimated even by standard molecular diagnostics. Sophisticated sampling and ul
Meta-analysis of exome array data identifies six novel genetic loci for lung function (Publications)
Background: Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. Methods: We carried out met
Drug combinations against soil-transmitted helminth infections (Publications)
The soil-transmitted helminths (STHs), Ascaris lumbricoides, hookworm and Trichuris trichiura are common in areas with warm and moist climates with little access to adequate water, sanitation, and hyg