Molecular epidemiology and antibiotic susceptibility of livestock <em>Brucella melitensis</em> isolates from Naryn Oblast, Kyrgyzstan (Publications)
The incidence of human brucellosis in Kyrgyzstan has been increasing in the last years and was identified as a priority disease needing most urgent control measures in the livestock population. The la
Do health workers' preferences influence their practices? Assessment of providers' attitude and personal use of new treatment recommendations for... (Publications)
ABSTRACT: BACKGROUND: Due to growing antimalarial drug resistance, Tanzania changed malaria treatment policies twice within a decade. First in 2001 chloroquine (CQ) was replaced by sulfadoxine-pyrimet
Quantifying quality of life and disability of patients with advanced schistosomiasis japonica (Publications)
BACKGROUND: The Chinese government lists advanced schistosomiasis as a leading healthcare priority due to its serious health and economic impacts, yet it has not been included in the estimates of schi
Adenosine kinase of <em>T. b. Rhodesiense</em> identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical... (Publications)
BACKGROUND: Human African trypanosomiasis (HAT), a major parasitic disease spread in Africa, urgently needs novel targets and new efficacious chemotherapeutic agents. Recently, we discovered that 4-[5
Performance of HRP-2 based rapid diagnostic test for malaria and its variation with age in an area of intense malaria transmission in southern... (Publications)
BACKGROUND: The use of malaria rapid diagnostic tests (RDTs) has been widely advocated to improve Plasmodium falciparum diagnosis, especially in settings where quality microscopy is not available. RDT
Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1 (Publications)
In a genome-wide screen for alpha-helical coiled coil motifs aiming at structurally defined vaccine candidates we identified PFF0165c. This protein is exported in the trophozoite stage and was named a
How much remains undetected? Probability of molecular detection of human <em>Plasmodia</em> in the field (Publications)
BACKGROUND: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detec
Clonal waves of <em>Neisseria</em> colonisation and disease in the African meningitis belt: eight- year longitudinal study in Northern Ghana (Publications)
BACKGROUND: The Kassena-Nankana District of northern Ghana lies in the African "meningitis belt" where epidemics of meningococcal meningitis have been reoccurring every eight to 12 years for the last