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1. Epidemiological estimate of growth reduction by ozone in <em>Fagus sylvatica L.</em> and <em>Picea abies</em> Karst.: sensitivity analysis and... (Publications)

   Epidemiological estimate of growth reduction by ozone in <em>Fagus sylvatica L.</em> and <em>Picea abies</em> Karst.: sensitivity analysis and comparison with experimental results

   Relevance:

   forest trees is based entirely on biomass data from fumigation experiments with saplings, mostly in open-top chambers. Extrapolation to mature forests asks, therefore, for validation, which may be performed

2. A randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants (Publications)

   A randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants

   Relevance:

   for use in young infants where routine therapeutic drug monitoring is not possible. METHODS: In an open, randomised, controlled trial, infants with suspected severe sepsis admitted to a Kenyan, rural district

3. A novel multiple-stage antimalarial agent that inhibits protein synthesis (Publications)

   A novel multiple-stage antimalarial agent that inhibits protein synthesis

   Relevance:

   and is essential for protein synthesis. This discovery of eEF2 as a viable antimalarial drug target opens up new possibilities for drug discovery

4. Imaging of <em>Plasmodium</em> liver stages to drive next-generation antimalarial drug discovery (Publications)

   Imaging of <em>Plasmodium</em> liver stages to drive next-generation antimalarial drug discovery

   Relevance:

   mg/kg) in rodent models of malaria and shows potent in vivo blood-stage therapeutic activity. The open source chemical tools resulting from our effort provide starting points for future drug discovery

5. A novel multiple-stage antimalarial agent that inhibits protein synthesis (Publications)

   A novel multiple-stage antimalarial agent that inhibits protein synthesis

   Relevance:

   and is essential for protein synthesis. This discovery of eEF2 as a viable antimalarial drug target opens up new possibilities for drug discovery

6. A randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants (Publications)

   A randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants

   Relevance:

   for use in young infants where routine therapeutic drug monitoring is not possible. METHODS: In an open, randomised, controlled trial, infants with suspected severe sepsis admitted to a Kenyan, rural district

7. Tolerability and efficacy of a pediatric granule formulation of artesunate-mefloquine in young children from Cameroon with uncomplicated falciparum... (Publications)

   Tolerability and efficacy of a pediatric granule formulation of artesunate-mefloquine in young children from Cameroon with uncomplicated falciparum malaria

   Relevance:

   pediatric formulation of artesunate and mefloquine (Artequin Pediatric) has been developed. In this open, non-comparative study in Cameroonian children with uncomplicated falciparum malaria, the safety and

8. Epidemiological estimate of growth reduction by ozone in <em>Fagus sylvatica L.</em> and <em>Picea abies</em> Karst.: sensitivity analysis and... (Publications)

   Epidemiological estimate of growth reduction by ozone in <em>Fagus sylvatica L.</em> and <em>Picea abies</em> Karst.: sensitivity analysis and comparison with experimental results

   Relevance:

   forest trees is based entirely on biomass data from fumigation experiments with saplings, mostly in open-top chambers. Extrapolation to mature forests asks, therefore, for validation, which may be performed

9. Hydra 2022: return of the interactive conference on helminth parasitology after the pandemic (Publications)

   Hydra 2022: return of the interactive conference on helminth parasitology after the pandemic

   Relevance:

   from August 28 to 2 September this year, with 100 delegates from 19 countries across the globe. Opening with Richard Davis’ keynote lecture, the conference included 12 wide-ranging presentation sessions

10. Model-based integration of genomics and metabolomics reveals SNP functionality in <em>Mycobacterium tuberculosis</em> (Publications)

    Model-based integration of genomics and metabolomics reveals SNP functionality in <em>Mycobacterium tuberculosis</em>

    Relevance:

    the antibiotic para-aminosalicylic acid. Our method is broadly applicable across microbial life, opening possibilities for the development of more selective treatment strategies.