Status of insecticide resistance in Papua New Guinea: an update from nation-wide monitoring of anopheles mosquitoes (Publications)
distribution of insecticide-treated nets. Here, we provide an update on phenotypic IR in four highly malaria-endemic areas of PNG. IR against deltamethrin, lambda-cyhalothrin, and dichlorodiphenyltrichloroethane
Conformational aspects in the design of inhibitors for serine hydroxymethyltransferase (SHMT): biphenyl, aryl sulfonamide, and aryl sulfone motifs (Publications)
Malaria remains a major threat to mankind due to the perpetual emergence of resistance against marketed drugs. Twenty-one pyrazolopyran-based inhibitors bearing terminal biphenyl, aryl sulfonamide, or
A Programmatic Analysis of integrated Community Case Management (iCCM): A Multicountry Systems-Wide Analysis of the RAcE (Rapid Access Expansion) iCCM... (Projects)
https://www.swisstph.ch/en/projects/project-detail/project/a-programmatic-analysis-of-integrated-community-case-management-iccm-a-multicountry-systems-wide-analysis-of-the-race-rapid-access-expansion-iccm-programme-in-sub-saharan-africa
provide children living in remote areas with access to case management for pneumonia, diarrhea, and malaria at the community level. The Rapid Access Expansion Programme (RAcE), steered by the World Health
Swiss TPH Awarded Four New Research Grants in Paediatric Health (News)
https://www.swisstph.ch/en/news/news-detail/news/swiss-tph-awarded-four-new-research-grants-in-paediatric-health
al Nets to Maximise Universal Access Long-lasting insecticidal nets (LLINs) are the mainstay of malaria control. However, more than 50% of people living in endemic areas are currently unprotected because [...] Health Institute and the Ministry of Health in Tanzania will develop a digital tool enabling national malaria control programs to improve planning for programmatic LLIN distribution, monitoring of LLIN quality [...] mosquito net lifespan will optimise resource use, increase the protection...
Medical Services (Page)
https://www.swisstph.ch/en/about/dir/medical-services
and, on behalf of the Federal Office of Public Health (FOPH), provides reference diagnosis for malaria and confirmatory diagnosis for other non-endemic parasitic diseases as part of the surveillance concept
Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay (Publications)
BACKGROUND: Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of
Maurer's clefts, the enigma of <em>Plasmodium falciparum</em> (Publications)
Plasmodium falciparum, the causative agent of malaria, completely remodels the infected human erythrocyte to acquire nutrients and to evade the immune system. For this process, the parasite exports more
Inhibition of <em>Plasmodium falciparum</em> Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles (Publications)
Malaria caused by the protozoan parasite Plasmodium falciparum (Pf) remains a major public health problem throughout the developing world. One molecular target that should receive more attention is the
Identification of nuclear proteins that differentially interact with <em>Plasmodium falciparum</em> var gene promoters (Publications)
PfEMP1 is responsible for both antigenic variation and cytoadherence of infected erythrocytes in malaria. Approximately 50 var genes per parasite genome code for this highly polymorphic surface protein
Mosquito nets and the poor: can social marketing redress inequities in access? (Publications)
Treated mosquito nets are a practical malaria control tool. However, implementation of efficient delivery mechanisms remains a challenge. We investigated whether social marketing of treated mosquito nets
