Field evaluation of spatial repellency of metofluthrin-impregnated plastic strips against <em>Anopheles gambiae</em> complex in Bagamoyo, coastal... (Publications)
collection compared with that for the controls). These low indices were observed despite the large openings found in Bagamoyo houses, which were predicted to have a considerable negative effect on the spatial
Vaccine potentials of an intrinsically unstructured fragment derived from the blood stage-associated <em>Plasmodium falciparum</em> protein PFF0165c (Publications)
antigen-specific antibody response with protection against clinical malaria. Within the predicted open reading frame of P. falciparum hypothetical protein PFF0165c, several segments with low hydrophobic
Synthesis, solution structure and immune recognition of an epidermal growth factor-like domain from <em>Plasmodium falciparum</em> merozoite surface... (Publications)
assays to cross-react with native MSP-1 on the surfaces of P. falciparum blood stage parasites. This opens the way for a medicinal chemistry-oriented approach to the study and optimization of the antigenicity
Soliciting diaries for "real-time" insights into the COVID-19 pandemic: methodological reflections on using digital technologies to engage the public (Publications)
adapt data gathering methods and build trust with diverse communities. While digital technologies open up new possibilities for public engagement, there is a need to think critically how data gathering
Field evaluation of a volatile pyrethroid spatial repellent and etofenprox treated clothing for outdoor protection against forest malaria vectors in... (Publications)
landing in Cambodia. A 7 × 7 Latin-square study was conducted over 49 collection nights in temporary open structures in Mondulkiri Province. All interventions substantially reduced Anopheles landing, with
Multicentre harmonization and co-analysis for large-scale environmental epidemiology : combining environmental exposure and health datasets (Publications)
interdisciplinary team of epidemiologists, statisticians, and computer scientists. I then show how these open-source and freely available tools can provide innovative solutions to facilitate collaborative ep [...] lung function and COPD in UK Biobank using two different air pollution exposure databases. Results An open-source software application suite and a standardized metadata model for observational cohort studies [...] and resources presented in this thesis provide the epidemiological...
Multicentre harmonization and co-analysis for large-scale environmental epidemiology : combining environmental exposure and health datasets (Publications)
interdisciplinary team of epidemiologists, statisticians, and computer scientists. I then show how these open-source and freely available tools can provide innovative solutions to facilitate collaborative ep [...] lung function and COPD in UK Biobank using two different air pollution exposure databases. Results An open-source software application suite and a standardized metadata model for observational cohort studies [...] and resources presented in this thesis provide the epidemiological...
An unusually broad series of seven cyclombandakamines, bridged dimeric naphthylisoquinoline alkaloids from the Congolese liana <em>Ancistrocladus... (Publications)
(electronic circular dichroism spectroscopy) and quantum chemical calculations. Compared to the 'open-chain' parent compound 9, these dimers displayed rather moderate antiplasmodial activities.
Early antischistosomal leads identified from<em> in vitro</em> and<em> in vivo</em> screening of the Medicines for Malaria Venture pathogen box (Publications)
expand the pool of potent molecules against schistosomiasis. The activity of 400 compounds from this open-access library was first screened in vitro on the larval stage of Schistosoma mansoni. The hits were
The good, the bad and the ugly: framing debates on nature in a One Health community (Publications)
Originating in medical and veterinary spheres, the One Health concept stands as an open call for collaboration also between these disciplines or professions and those of environmental and social science