First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials (Publications)
progression to Phase 2a proof-of concept studies in the target population of acute uncomplicated malaria
Multiple parasite infections and their relationship to self-reported morbidity in a community of rural Côte d'Ivoire (Publications)
soil-transmitted helminths and intestinal protozoa. Giemsa-stained blood smears were analysed for malaria parasites. A questionnaire was administered for collection of demographic information and self-reported
Field issues related to effectiveness of insecticide-treated nets in Tanzania (Publications)
impregnated with pyrethroid insecticides have become one of the most promising interventions to prevent malaria in highly endemic areas. Despite the large body of experience documenting their health impact and
Recours aux soins et utilisation des services de santé à Nouakchott (Mauritanie): inégalités spatiales ou pesanteurs sociales? (Publications)
or weight loss) seen to suggest more serious diseases, such as tuberculosis, meningitis or severe malaria. Geographic accessibility of health services was relatively good (70 %). It was the economic, so
The influence of physiological status on age prediction of <em>Anopheles arabiensis</em> using near infra-red spectroscopy (Publications)
BACKGROUND: Determining the age of malaria vectors is essential for evaluating the impact of interventions that reduce the survival of wild mosquito populations and for estimating changes in vectorial
Prevalence and factors associated with convulsive status epilepticus in Africans with epilepsy (Publications)
, acute encephalopathy, previous hospitalization, and presence of antibody titers to falciparum malaria and HIV; these differed across sites. Burns (15%), lack of education (49%), being single (77%), and
Emergence of artemisinin-resistant <em>Plasmodium falciparum</em> with <em>kelch13 </em>C580Y mutations on the island of New Guinea (Publications)
nt Plasmodium falciparum carrying the C580Y mutation in the kelch13 gene is a growing threat to malaria elimination in Southeast Asia, but there is no evidence of their spread to other regions. We conducted
Influence of sugar availability and indoor microclimate on survival of <em>Anopheles gambiae</em> (Diptera: Culicidae) under semifield conditions in... (Publications)
served to increase survival potential of vectors beyond ages at which they are old enough to transmit malaria
Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials (Publications)
20 mg/kg (4 patients; CR: 75%, ERR: 96%). CONCLUSIONS/SIGNIFICANCE: Artemether, administered at malaria treatment regimens, shows no or only little effect against fascioliasis, and hence does not represent
Discovery of dual function acridones as a new antimalarial chemotype (Publications)
resistance, and both are undesirable in effective long-term strategies against multi-drug-resistant malaria. Haem remains an immutable and vulnerable target, because it is not parasite-encoded and its det
