<em>Plasmodium falciparum</em> heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors (Publications)
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded by
Distribution and risk factors for <em>Plasmodium</em> and helminth co-infections: a cross-sectional survey among children in Bagamoyo district,... (Publications)
vermicularis, Trichuris trichura), schistosoma species and Wuchereria bancrofti. Blood slides and malaria rapid diagnostic tests (mRDTs) were utilized for Plasmodium diagnosis. RESULTS: Out of 992 children
Prevalence of <em>Schistosoma </em>mono- and co-infections with multiple common parasites and associated risk factors and morbidity profile among... (Publications)
selected individuals, aged 18-90 years, provided blood, stool and urine samples for the diagnosis of malaria and helminth infections. Stool samples were subjected to the Kato-Katz technique for detection of
Causes of acute undifferentiated fever and the utility of biomarkers in Chiangrai, northern Thailand (Publications)
continue to contribute substantially to the febrile disease burden throughout Southeast Asia while malaria is declining. Recently, there has been increasing focus on biomarkers (i.e. C-reactive protein (CRP)
Cell penetration, herbicidal activity, and <em>in-vivo</em>-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived... (Publications)
in-vitro investigations with the octaarginine salt of the phosphonate fosmidomycin (herbicide and anti-malaria drug) have shown a 40-fold parasitaemia inhibition with P.falciparum, compared to fosmidomycin alone
Günther Fink is the new Eckenstein-Geigy Professor for Epidemiology and Household Economy (News)
https://www.swisstph.ch/en/news/news-detail/news/guenther-fink-is-the-new-eckenstein-geigy-professor-for-epidemiology-and-household-economy
programmes in Nigeria. He has also collaborated in major health programmes to reduce the burden of malaria in several African countries as well as in initiatives to improve infant nutrition and early child
Validation of <em>Plasmodium falciparum</em> dUTPase as the target of 5'-tritylated deoxyuridine analogues with anti-malarial activity (Publications)
BACKGROUND: Malaria remains as a major global problem, being one of the infectious diseases that engender highest mortality across the world. Due to the appearance of resistance and the lack of an effective
Gianpaolo Pontiggia (People)
https://www.swisstph.ch/en/staff/profile/people/gianpaolo-pontiggia
and public health. Professional activities at Swiss TPH Project manager working on international Malaria’s projects funded by international donors such as the Melinda and Bill Gates Foundation, Clinton Health
Climate Change (Page)
https://www.swisstph.ch/en/topics/environment-and-health/climate-change
2050, 6 billion people will be at risk of one or several of the ‘big 7’ climate-related diseases: malaria, haemorrhagic fevers, schistosomiasis, human African trypanosomiasis, Chagas disease, leishmaniasis [...] well as water related diseases. The second phase is focussig on the people's abilities to cope with malaria and bilharzia infections on the fringes of the Sahelian belt. Heavy rains and floods, associated
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
Far from the baneful impact of the so-called “big three” (HIV/AIDS, tuberculosis and malaria), schistosomiasis and other worm infections, such as the soil-transmitted helminths (STH) for example, have [...] each, both compiled and provided by the non-profit product development partnership Medicines for Malaria Venture (MMV). One library, the Pathogen Box, was composed of drug-like molecules with already-known
