wIRA: hyperthermia as a treatment option for intracellular bacteria, with special focus on Chlamydiae and Mycobacteria (Publications)
infections are presented. Finally, technical aspects of using wIRA in patients are critically reviewed and open questions driving future research are highlighted. In conclusion, wIRA is a promising tool for reducing
A qualitative appraisal of stakeholder reactions to a tool for burden of disease-based health system budgeting in Ghana (Publications)
were drawn from the national, regional, and district levels of the health system and interviewed in open-ended discussions about their reactions to DiHPART and suggestions for systems development. RESULTS:
Assessing the relationship between environmental factors and malaria vector breeding sites in Swaziland using multi-scale remotely sensed data (Publications)
with high spatial resolution has often resulted in analyses being conducted at coarse scales using open-source, archived remotely sensed data. In the present study, spatial prediction of potential breeding
Modeling indoor air pollution of outdoor origin in homes of SAPALDIA subjects in Switzerland (Publications)
indoors were between 30% and 66%, the highest one was observed for PMabsorbance. A modifying effect of open windows was found for NO2 and the ultrafine particle number concentration. Cooking was associated
Short course amphotericin B in addition to sertraline and fluconazole for treatment of HIV-associated cryptococcal meningitis in rural Tanzania (Publications)
activity against Cryptococcus and bi-directional synergy with fluconazole. METHODS: We conducted an open label clinical trial to assess the safety and efficacy of sertraline 400 mg/day and fluconazole 1200
Epidemiologie, Klinik, Diagnostik und Therapie von Infektionen durch <em>Mycobacterium chimaera</em> (Publications)
increasingly reported over the past few years. Most infections occurred in patients who had undergone open-chest cardiothoracic surgery. Epidemiological and molecular studies showed that transmission of M
Integrating standardized whole genome sequence analysis with a global <em>Mycobacterium tuberculosis</em> antibiotic resistance knowledgebase (Publications)
from MTBC sequence data. Stringent thresholds and quality control measures were incorporated in this open source tool. The pipeline was validated using a well-characterized dataset of 90 diverse MTBC isolates
<em>Trypanosoma cruzi</em> STIB980: a TcI strain for drug discovery and reverse genetics (Publications)
This resulted in a high-quality nuclear haplotype assembly of 28 Mb in 400 contigs, containing 10,043 open-reading frames with a median length of 1077 bp. We believe that T. cruzi STIB980 is a useful addition
Functional characterization and phenotypic monitoring of human hematopoietic stem cell expansion and differentiation of monocytes and macrophages by... (Publications)
e blood monocytes-derived from HSC-derived macrophages. To conclude, we propose that this method opens new avenues to distinguish the impact of human genetics on the dysregulated biological properties
Global health essentials (Publications)
Development Goals (SDG) 2030 agenda. Subdivided into 11 parts, devoted each to a macro-topic, the book opens with an introduction to Global Health followed by an overview of the global burden of disease – from
