Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood (Publications)
BACKGROUND: European cross-sectional studies have suggested that prenatal and postnatal farm exposure decreases the risk of allergic diseases in childhood. Underlying immunologic mechanisms are still
Health-related quality of life does not explain the protective effect of farming on allergies (Publications)
To cite this article: Stocklin L, Loss G, von Mutius E, Genuneit J, Horak E, Braun-Fahrlander C. Health-related quality of life does not explain the protective effect of farming on allergies. Pediatr
Histone methyltransferase inhibitors are orally bioavailable, fast acting molecules with activity against different species causing malaria in humans (Publications)
Current antimalarials are under continuous threat due to the relentless development of drug resistance by malaria parasites. We previously reported promising in vitro parasite killing activity with th
Consumption of unprocessed cow's milk protects infants from common respiratory infections (Publications)
BACKGROUND: Breast-feeding is protective against respiratory infections in early life. Given the co-evolutionary adaptations of humans and cattle, bovine milk might exert similar anti-infective effect
Gene-environment interaction for childhood asthma and exposure to farming in Central Europe (Publications)
BACKGROUND: Asthma is a disease in which both genetic and environmental factors play important roles. The farming environment has consistently been associated with protection from childhood asthma and
Phosphorylation of the ribosomal protein S6, a marker of mTOR pathway activation, is strongly increased in hypertrophic scars and keloids [Research... (Publications)
Hypertrophic scars and keloids are fibrous overgrowths, which may develop in response to skin injury, but spontaneous forms also exist. It has been reported that tissue extracts from keloids contain e
Mass screening and treatment on the basis of results of a <em>Plasmodium</em> <em>falciparum</em>-specific rapid diagnostic test did not reduce... (Publications)
BACKGROUND: Seasonal increases in malaria continue in hotspots in Zanzibar. Mass screening and treatment (MSAT) may help reduce the reservoir of infection; however, it is unclear whether rapid diagnos
Surveillance and response: tools and approaches for the elimination stage of neglected tropical diseases (Publications)
The presentation of the World Health Organization (WHO)'s Roadmap for neglected tropical diseases (NTDs) in January 2012 raised optimism that many NTDs can indeed be eliminated. To make this happen, t