Comparison of biomarker based Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and conventional methods in... (Publications)
BACKGROUND: MALDI-TOF MS is an analytical method that has recently become integral in the identification of microorganisms in clinical laboratories. It relies on databases that majorly employ pattern
The association of a variant in the cell cycle control gene CCND1 and obesity on the development of asthma in the Swiss SAPALDIA study (Publications)
Objective. The molecular mechanisms underlying the association between obesity (BMI > /= 30 kg/m(2)) and asthma are poorly understood. Since shifts in the fate of bronchial cells due to low-grade syst
Asthma and the menopause: a systematic review and meta-analysis (Publications)
OBJECTIVE: To review the available literature to determine whether the menopausal transition is associated with asthma incidence.METHODS: We performed a systematic review and meta-analysis of cohort a
Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population (Publications)
ABSTRACT: BACKGROUND: Few epidemiologic studies have assessed health-related quality of life (HRQL) of asthma patients from a general population and it is unclear which instrument is best suitable for
Joint effect of obesity and TNFA variability on asthma: two international cohort studies (Publications)
Obesity is a risk factor for asthma. Adipose tissue expresses pro-inflammatory molecules including tumour necrosis factor (TNF), and levels of TNF are also related to polymorphisms in the TNF-alpha (T
Defining the next generation of <em>Plasmodium vivax</em> diagnostic tests for control and elimination: target product profiles (Publications)
The global prevalence of malaria has decreased over the past fifteen years, but similar gains have not been realized against Plasmodium vivax because this species is less responsive to conventional ma
Development and evaluation of a bioinformatics approach for designing molecular assays for viral detection (Publications)
BACKGROUND: Viruses belonging to the Flaviviridae and Bunyaviridae families show considerable genetic diversity. However, this diversity is not necessarily taken into account when developing diagnosti
Effectiveness of a 10-day melarsoprol schedule for the treatment of late-stage human African trypanosomiasis: confirmation from a multinational study... (Publications)
BACKGROUND: Treatment of late-stage human African trypanosomiasis (HAT) with melarsoprol can be improved by shortening the regimen. A previous trial demonstrated the safety and efficacy of a 10-day tr